Evidence map›Paper›PMID 37314874›Full record

ReviewAnnual review of analytical chemistry (Palo Alto, Calif.)2023

Nanoparticles for Interrogation of Cell Signaling.

Seonik Lee, Mengchi Jiao, Zihan Zhang, Yan Yu

Abstract readReview
In one paragraph

Review in Annual review of analytical chemistry (Palo Alto, Calif.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Seonik LeeDepartment of Chemistry, Indiana University, Bloomington, Indiana, USA; email: yy33@iu.edu.
Mengchi JiaoDepartment of Chemistry, Indiana University, Bloomington, Indiana, USA; email: yy33@iu.edu.
Zihan ZhangDepartment of Chemistry, Indiana University, Bloomington, Indiana, USA; email: yy33@iu.edu.
Yan YuDepartment of Chemistry, Indiana University, Bloomington, Indiana, USA; email: yy33@iu.edu.

Funding

Unravelling Mechanisms of Endosomal Signaling with Designer NanomaterialsR35GM124918 · NIGMS · WASHINGTON UNIVERSITY · PI Yan Yu · 2017 to 2026
$3.8M
NIGMS NIH HHS R35 GM124918
6 · The paper itself

Abstract

Cell functions rely on signal transduction-the cascades of molecular interactions and biochemical reactions that relay extracellular signals to the cell interior. Dissecting principles governing the signal transduction process is critical for the fundamental understanding of cell physiology and the development of biomedical interventions. The complexity of cell signaling is, however, beyond what is accessible by conventional biochemistry assays. Thanks to their unique physical and chemical properties, nanoparticles (NPs) have been increasingly used for the quantitative measurement and manipulation of cell signaling. Even though research in this area is still in its infancy, it has the potential to yield new, paradigm-shifting knowledge of cell biology and lead to biomedical innovations. To highlight this importance, we summarize in this review studies that pioneered the development and application of NPs for cell signaling, from quantitative measurements of signaling molecules to spatiotemporal manipulation of cell signal transduction.

Indexed as

NanoparticlesSignal TransductionBiological AssayKnowledgeLaw Enforcementcell signalingintracellular sensingmagnetic manipulationnanoparticlesoptical manipulationquantitative imaging

Identifiers

PMID37314874
PMCPMC10627408

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.