Evidence map›Paper›PMID 37314623›Full record

ArticleMolecular and cellular biochemistry2024

Exogenous interleukin-1 beta stimulation regulates equine tenocyte function and gene expression in three-dimensional culture which can be rescued by pharmacological inhibition of interleukin 1 receptor, but not nuclear factor kappa B, signaling.

Ross Eric Beaumont, Emily Josephine Smith, Lexin Zhou, Neil Marr, Chavaunne T Thorpe, Deborah Jane Guest

Abstract read
In one paragraph

Article in Molecular and cellular biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ross Eric BeaumontClinical Sciences and Service, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, AL9 7TA, Herts, UK. robeaumont@rvc.ac.uk.
Emily Josephine SmithClinical Sciences and Service, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, AL9 7TA, Herts, UK.
Lexin ZhouClinical Sciences and Service, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, AL9 7TA, Herts, UK.
Neil MarrComparative Biomedical Sciences, Royal Veterinary College, Royal College Street, London, NW1 0TU, UK.
Chavaunne T ThorpeComparative Biomedical Sciences, Royal Veterinary College, Royal College Street, London, NW1 0TU, UK.
Deborah Jane GuestClinical Sciences and Service, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, AL9 7TA, Herts, UK.

Funding

Horserace Betting Levy Board VET/RS/257Petplan Charitable Trust S19-747-786Versus Arthritis 21216/22607Wellcome Trust
6 · The paper itself

Abstract

We investigated how Interleukin 1 beta (IL-1β) impacts equine tenocyte function and global gene expression in vitro and determined if these effects could be rescued by pharmacologically inhibiting nuclear factor-κB (NF-

Indexed as

Interleukin-1betaNF-kappa BSignal TransductionTenocytesAnimalsCell Culture Techniques, Three DimensionalCells, CulturedGene Expression RegulationHorsesReceptors, Interleukin-1Interleukin-1betaNF-kappa BReceptors, Interleukin-1CytokineEquineHorseInflammationMusculoskeletalTendon

Identifiers

PMID37314623
PMCPMC11116237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.