Evidence map›Paper›PMID 37314549›Full record

ArticleCell regeneration (London, England)2023

Standard: Human intestinal organoids.

Yalong Wang, Hanqing Lin, Lianzheng Zhao, Fan Hong, Jie Hao, Zhen Zhang, Weiqi Sheng, Linhong Song, Chu-Xia Deng, Bing Zhao and 16 more

Abstract readEditorial
In one paragraph

Article in Cell regeneration (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Standard: Human gastric organoids.Cell regeneration (London, England) · 2025
    Article
  7. Standardization of Stem Cell and Regenerative Medicine in China.Advances in experimental medicine and biology · 2025
    Review
  8. Standard: human intestine-on-a-chip.Cell regeneration (London, England) · 2024
    Article
  9. Guidelines for Manufacturing and Application of Organoids: Skin.International journal of stem cells · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Yalong Wang *The State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Hanqing Lin *D1Med Technology (Shanghai) Inc, Shanghai, 201802, China.
Lianzheng Zhao *The State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Fan Hong *Guangzhou Laboratory, Guangzhou, 510005, China.
Jie HaoState Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, National Stem Cell Resource Center, Chinese Academy of Sciences, Beijing, 100101, China.
Zhen ZhangDepartment of Radiation Oncology and Cancer Institute, Fudan University Shanghai Cancer Center Fudan University, Shanghai, 200032, China.
Weiqi ShengDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Linhong SongSichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, 610072, China.
Chu-Xia DengCancer Centre, Faculty of Health Sciences, University of Macau, Macau, 999078, SAR, China.
Bing ZhaoState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, 200438, China.
Jiani CaoState Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, National Stem Cell Resource Center, Chinese Academy of Sciences, Beijing, 100101, China.
Lei WangState Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, National Stem Cell Resource Center, Chinese Academy of Sciences, Beijing, 100101, China.
Liu WangState Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, National Stem Cell Resource Center, Chinese Academy of Sciences, Beijing, 100101, China.
Lingmin LiangState Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, National Stem Cell Resource Center, Chinese Academy of Sciences, Beijing, 100101, China.
Wenli Kelly ChenChina Innovation Center of Roche, Li Shi Zhen Road, Pudong, Shanghai, 201203, China.
Chunping YuEli Lilly and Company, Pudong, Shanghai, 201203, China.
Zhijian SunK2 Oncology Co., Ltd, KeChuang Street, Beijing, 100176, China.
Yingying YangQilu Pharmaceutical Co., Ltd, Jinan, 250104, China.
Changlin WangInstitute of Clinical Science, Zhongshan Hospital, Fudan University, Shanghai, 200433, China.
Yong ZhangChinese Society for Stem Cell Research, Shanghai, 200032, China.
Qiyuan LiInstitute of Clinical Science, Zhongshan Hospital, Fudan University, Shanghai, 200433, China.
Ka LiInstitute of Clinical Science, Zhongshan Hospital, Fudan University, Shanghai, 200433, China.
Aijin MaInstitute of Clinical Science, Zhongshan Hospital, Fudan University, Shanghai, 200433, China. 783869855@qq.com.
Tongbiao ZhaoState Key Laboratory of Stem Cell and Reproductive Biology, Institute for Stem Cell and Regeneration, Institute of Zoology, National Stem Cell Resource Center, Chinese Academy of Sciences, Beijing, 100101, China. tbzhao@ioz.ac.cn.
Guoqiang HuaD1Med Technology (Shanghai) Inc, Shanghai, 201802, China. guoqianghua@fudan.edu.cn.
Ye-Guang ChenThe State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China. ygchen@tsinghua.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organoids have attracted great interest for disease modelling, drug discovery and development, and tissue growth and homeostasis investigations. However, lack of standards for quality control has become a prominent obstacle to limit their translation into clinic and other applications. "Human intestinal organoids" is the first guideline on human intestinal organoids in China, jointly drafted and agreed by the experts from the Chinese Society for Cell Biology and its branch society: the Chinese Society for Stem Cell Research. This standard specifies terms and definitions, technical requirements, test methods, inspection rules for human intestinal organoids, which is applicable to quality control during the process of manufacturing and testing of human intestinal organoids. It was originally released by the Chinese Society for Cell Biology on 24 September 2022. We hope that the publication of this standard will guide institutional establishment, acceptance and execution of proper practical protocols and accelerate the international standardization of human intestinal organoids for applications.

Identifiers

PMID37314549
PMCPMC10267020

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.