Evidence map›Paper›PMID 37314545›Full record

ArticleAnnals of surgical oncology2023

Associations Between Hospital Volume and Overall Survival After Surgery in Older Patients with Breast Cancer.

Sam Z Thalji, Chandler S Cortina, Julia Frebault, Youngjoo Cho, Abigail Thorgerson, Carmen R Bergom, Chiang-Ching Huang, Amanda L Kong

Abstract read
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Article in Annals of surgical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sam Z ThaljiDivision of Surgical Oncology, Department of Surgery, Medical College of Wisconsin, 8701 W, Watertown Plank Road, Milwaukee, WI, USA.
Chandler S CortinaDivision of Surgical Oncology, Department of Surgery, Medical College of Wisconsin, 8701 W, Watertown Plank Road, Milwaukee, WI, USA.
Julia FrebaultDivision of Surgical Oncology, Department of Surgery, Medical College of Wisconsin, 8701 W, Watertown Plank Road, Milwaukee, WI, USA.
Youngjoo ChoJoseph J. Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
Abigail ThorgersonJoseph J. Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
Carmen R BergomDepartment of Radiation Oncology, Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA.
Chiang-Ching HuangJoseph J. Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
Amanda L KongDivision of Surgical Oncology, Department of Surgery, Medical College of Wisconsin, 8701 W, Watertown Plank Road, Milwaukee, WI, USA. akong@mcw.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh-volume hospitals (HVHs) are associated with improved overall survival (OS) following surgery for breast cancer compared with low-volume hospitals (LVHs). We examined this association in patients age ≥ 80 years and described patient and treatment characteristics associated with HVHs. PATIENTS AND

methodsThe National Cancer Database was queried for women age ≥ 80 years who underwent surgery for stage I-III breast cancer between 2005 and 2014. Hospital volume was defined as the average number of cases during the year of the patient's index operation and the year prior. Hospitals were categorized into HVHs and LVHs using penalized cubic spline analysis of OS. A cutoff of ≥ 270 cases/year defined HVHs.

resultsAmong 59,043 patients, 9110 (15%) were treated at HVHs and 49,933 (85%) at LVHs. HVHs were associated with more non-Hispanic Black and Hispanic patients, earlier stage disease (stage I 54.9% vs. 52.6%, p < 0.001), higher rates of breast-conserving surgery (BCS) (68.3% vs. 61.4%, p < 0.001), and adjuvant radiation (37.5% vs. 36.1%, p = 0.004). Improved OS was associated with surgery at a HVH (HR 0.85, CI 0.81-0.88), along with receipt of adjuvant chemotherapy (HR 0.73, CI 0.69-0.77), endocrine therapy (HR 0.70, CI 0.68-0.72), and radiation (HR 0.66, CI 0.64-0.68).

conclusionsAmong patients with breast cancer age ≥ 80 years, undergoing surgery at a HVH was associated with improved OS. Patients who completed surgery at HVHs had earlier stage disease and more commonly received adjuvant radiation when appropriate. Processes of care at HVHs should be identified to improve outcomes in all settings.

Indexed as

Breast NeoplasmsAgedAged, 80 and overFemaleHospitals, High-VolumeHospitals, Low-VolumeHumans

Identifiers

PMID37314545

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.