Evidence map›Paper›PMID 37314394›Full record

ReviewExpert review of anti-infective therapy

New therapeutic strategies for

Matthéo Alcaraz, Thomas E Edwards, Laurent Kremer

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of anti-infective therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Leucine auxotrophic marker for genetic manipulation ofApplied and environmental microbiology · 2026
    Article
  2. Article
  3. Diversity of FAAL enzymes and prediction of their substrate specificity using FAALPred.Protein science : a publication of the Protein Society · 2026
    Article
  4. Article
  5. An enoyl-ACP reductase inhibitor, NITD-916, expresses anti-Antimicrobial agents and chemotherapy · 2025
    Article
  6. Article
  7. Clinical Trials involvingThe Ulster medical journal · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Matthéo AlcarazCentre National de la Recherche Scientifique UMR 9004, Institut de Recherche En Infectiologie de Montpellier (IRIM), Université de Montpellier, Montpellier, France.
Thomas E EdwardsDivision of Structural Biology, UCB BioSciences, Bainbridge Island, WA, USA.ORCID 0000-0002-0474-8003
Laurent KremerCentre National de la Recherche Scientifique UMR 9004, Institut de Recherche En Infectiologie de Montpellier (IRIM), Université de Montpellier, Montpellier, France.ORCID 0000-0002-6604-4458
Center for Infectious Disease Research · USInserm · FRUniversité de Montpellier · FR

Funding

NIAID NIH HHS HHSN272201700059C
6 · The paper itself

Abstract

introductionTreatment options against AREAS COVERED: Herein, the authors review the role of the MmpL3 membrane protein and the enoyl-ACP reductase InhA involved in the transport and synthesis of mycolic acids, respectively. They discuss their importance as two major vulnerable drug targets in EXPERT OPINION: There is an increasing body of evidence validating the mycolic acid pathway as an attractive drug target to be further exploited for

Indexed as

Lung DiseasesMycobacterium abscessusMycobacterium Infections, NontuberculousMycobacterium tuberculosisAnimalsAntitubercular AgentsBacterial ProteinsHumansMicrobial Sensitivity TestsMycolic AcidsZebrafishAntitubercular AgentsBacterial ProteinsMycolic AcidsChemotherapyInhAInhibitionMmpL3Mycobacterium abscessusMycolic acid

Identifiers

PMID37314394
PMCPMC10529309
OpenAlexW4380576587

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.