ArticleThe Journal of international medical research2023
Association between neutrophil percentage-to-albumin ratio and 28-day mortality in Chinese patients with sepsis.
Article in The Journal of international medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Prognostic value of hematological markers for anastomotic leakage diagnosed after postoperative day 5 following laparoscopic surgery for colorectal cancer.BMC surgery · 2026Article
- Impact of sex on the association between neutrophil percentage-to-albumin ratio and mortality in perioperative patients with chronic kidney disease: a retrospective analysis of the INSPIRE database.Perioperative medicine (London, England) · 2026Article
- Neutrophil-Percentage-to-Albumin Ratio and Monocyte-to-Albumin Ratio: Utility of the Combined Biomarkers in the Prediction of 30-Day Mortality in Male Diabetes Patients Over 80 Years Old with Bloodstream Infections.Clinical interventions in aging · 2026Article
- Association between the neutrophil-to-albumin ratio and mortality in patients undergoing tracheal intubation: a retrospective cohort study.Frontiers in medicine · 2026Article
- Association Between Neutrophil Percentage-to-Albumin Ratio (NPAR) and Risk of Stroke in Patients With Hypertension: A Cohort Study.Journal of clinical hypertension (Greenwich, Conn.) · 2026Article
- Development and Validation of a Nomogram Model to Predict the Risk of Severe Pneumonia in Children with Pneumococcal Infection.Infection and drug resistance · 2026Article
- Association of NPAR with 90-day mortality in predominantly acute-on-chronic liver failure.Frontiers in medicine · 2026Article
- Neutrophil Percentage-to-Albumin Ratio: Unveiling a New Perspective on Mortality Risk in Intensive Care Unit Asthma Patients-A Retrospective Cohort Study.Mediators of inflammation · 2026Article
- Associations between the creatinine/cystatin C ratio and 28-day mortality in critically ill patients with sepsis: a retrospective cohort study.Frontiers in nutrition · 2026Article
- Association between serum uric acid to albumin ratio and all-cause mortality in critically ill patients with sepsis: a retrospective study.BMC infectious diseases · 2025Article
- Neutrophil Percentage-to-Albumin Ratio Predicts Contrast-Induced Acute Kidney Injury in Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention.Journal of clinical medicine · 2025Article
- Inflammation-Based Hematologic Indices as Prognostic Markers in Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension: A Hypothesis-Generating Registry Study.International journal of molecular sciences · 2025Article
- Preoperative neutrophil percentage-to-albumin ratio as a postoperative AKI predictor in non-cardiac surgery: a retrospective cohort secondary analysis.Scientific reports · 2025Article
- Association of neutrophil percentage-to-albumin ratio with all-cause and respiratory disease-related mortality in US adults with asthma.BMC pulmonary medicine · 2025Article
- Association of neutrophil-percentage-to-albumin ratio with all-cause and cardiovascular mortality in patients with diabetes and prediabetes from the NHANES 1999-2018.Scientific reports · 2025Article
- Neutrophil-to-lymphocyte-to-albumin ratio as a prognostic marker for mortality in sepsis and septic shock in Vietnam.Acute and critical care · 2025Article
- Neutrophil Percentage-to-Albumin Ratio as a Prognostic Marker in Pneumonia Patients Aged 80 and Above in Intensive Care.Journal of clinical medicine · 2025Article
- Correlation of neutrophil percentage-to-albumin ratio with lung function in American adults: a population study.BMC pulmonary medicine · 2025Article
- Associations between neutrophil-percentage-to-albumin ratio level and all-cause mortality and cardiovascular disease-cause mortality in diabetes population.BMC public health · 2025Article
- Association between neutrophil-percentage-to-albumin ratio and periodontitis: insights from a population-based study.Frontiers in nutrition · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the association between neutrophil percentage-to-albumin ratio (NPAR) and 28-day mortality in severely ill Chinese patients with sepsis.
methodsIn this retrospective, single-centre study, sepsis patients admitted to the ICU of the Affiliated Hospital of Jining Medical University between May 2015 and December 2021 were retrospectively analysed. The relationship between NPAR and 28-day mortality was examined using Cox proportional-hazards model.
resultsIn total, 741 patients with sepsis were included. Multivariate analysis, adjusted for age, sex, body mass index (BMI), smoking and alcohol drinking history, showed an association between elevated NPAR and a high risk of 28-day mortality. After removal of additional confounders, moderate and high NPAR values remained significantly associated with 28-day mortality in comparison with low NPAR values (tertile 2 vs 1: HR, 95% CI: 1.42, 1.06-1.90; tertile 3 vs 1: HR, 95% CI: 1.35, 1.00-1.82). Survival curves stratified by NPAR groups showed that high NPAR levels had lower survival probabilities than lower NPAR levels. Subgroup analysis did not show any significant interactions between NPAR and 28-day mortality.
conclusionsElevated NPAR values were linked to increased 28-day mortality in severely ill Chinese patients with sepsis. The findings require verification by large, prospective, multi-centre studies.
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