Observational studyJournal of the American Heart Association2023
Biomarkers and Echocardiographic Predictors of Cardiovascular Outcome in Patients With Chronic Chagas Disease.
Observational study in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Vaccines against chronicExpert review of vaccines · 2026Review
- Chagas-specific Death and Competing Risk of Mortality in Chile: A Nationwide Retrospective Cohort Study, 2007-2021.Open forum infectious diseases · 2026Article
- Left Atrial Coupling Indexes as New Mortality Predictors in Chronic Chagas Disease.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Global longitudinal strain as a predictor of outcomes in chronic Chagas´ cardiomyopathy.PLoS neglected tropical diseases · 2025Article
- Predictors of Incident Heart Failure in Patients With Chronic Chagas Disease Cardiomyopathy.Echocardiography (Mount Kisco, N.Y.) · 2025Observational
- PBMC transcriptomic signatures reflect Trypanosoma cruzi strain diversity and trained immunity in chronically infected macaques.JCI insight · 2025Article
- Myocardial work in Chagas disease: comparative analysis with conventional parameters in different cardiac clinical stages.Frontiers in cardiovascular medicine · 2025Article
- A guide for the generation of repositories of clinical samples for research on Chagas disease.PLoS neglected tropical diseases · 2024Article
- Absolute Lymphocyte Count: a Predictor of Positive Serum PCR for Trypanosoma cruzi in Patients with Chagas Disease Undergoing Heart Transplantation.Arquivos brasileiros de cardiologia · 2024Observational
- Exploring the Historical Background and Clinical Implications of Electrocardiogram in the Context of Chagas Disease Research.Revista da Sociedade Brasileira de Medicina Tropical · 2023Review
- Predictors of Trypanosoma cruzi PCR positivity in patients with chronic Chagas disease.Memorias do Instituto Oswaldo Cruz · 2023Observational
Corrections and comments
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Authors and funding
22 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Chagas disease (CD) presents an ominous prognosis. The predictive value of biomarkers and new echocardiogram parameters in adjusted models have not been well studied. Methods and Results There were 361 patients with chronic CD (57.6% men, 61±11 years of age, clinical forms: indeterminate 27.1%, cardiac 56.6%, digestive 3.6%, cardiodigestive 12.7%) included in this single-center, observational, prospective longitudinal study. Echocardiographic evaluation included strain analyses of left atrial, left ventricular (LV), and right ventricular and 3-dimensional analyses of left atrial and LV volumes. Biomarkers included cardiac troponin I, brain natriuretic peptide, transforming growth factor β1, tumor necrosis factor, matrix metalloproteinases, and
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.