Evidence map›Paper›PMID 37313820›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2023

[Embedded 3D printing of porous silicon orbital implants and its surface modification].

H Zhao, Y Wang, Y Wang, H Gong, F Yinjun, X Cui, J Zhang, W Huang

Open access · greenAbstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

H ZhaoDepartment of Human Anatomy, School of Basic Medical Sciences, Guangdong Medical University, Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, Dongguan 523808, China.
Y WangNational Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangdong Provincial Key Laboratory of Digital Medical and Biomechanics, Guangdong Engineering Research Center for Translation of Medical 3D Printing Application, Guangzhou 510515, China.
Y WangGuangdong Provincial People's Hospital Affiliated to Southern Medical University, Guangdong Academy of Medical Science, Guangzhou 510080, China.
H GongNational Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangdong Provincial Key Laboratory of Digital Medical and Biomechanics, Guangdong Engineering Research Center for Translation of Medical 3D Printing Application, Guangzhou 510515, China.
F YinjunNational Key Discipline of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangdong Provincial Key Laboratory of Digital Medical and Biomechanics, Guangdong Engineering Research Center for Translation of Medical 3D Printing Application, Guangzhou 510515, China.
X CuiDepartment of Human Anatomy, School of Basic Medical Sciences, Guangdong Medical University, Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, Dongguan 523808, China.
J ZhangDepartment of Human Anatomy, School of Basic Medical Sciences, Guangdong Medical University, Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, Dongguan 523808, China.
W HuangDepartment of Human Anatomy, School of Basic Medical Sciences, Guangdong Medical University, Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, Dongguan 523808, China.
Guangdong Medical College · CNSouthern Medical University · CNGuangdong Academy of Medical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo prepare customized porous silicone orbital implants using embedded 3D printing and assess the effect of surface modification on the properties of the implants.

methodsThe transparency, fluidity and rheological properties of the supporting media were tested to determine the optimal printing parameters of silicone. The morphological changes of silicone after modification were analyzed by scanning electron microscopy, and the hydrophilicity and hydrophobicity of silicone surface were evaluated by measuring the water contact angle. The compression modulus of porous silicone was measured using compression test. Porcine aortic endothelial cells (PAOECs) were co-cultured with porous silicone scaffolds for 1, 3 and 5 days to test the biocompatibility of silicone. The local inflammatory response to subcutaneous porous silicone implants was evaluated in rats.

resultsThe optimal printing parameters of silicone orbital implants were determined as the following: supporting medium 4% (mass ratio), printing pressure 1.0 bar and printing speed 6 mm/s. Scanning electron microscopy showed that the silicone surface was successfully modified with polydopamine and collagen, which significantly improved hydrophilicity of the silicone surface (

conclusionPoprous silicone orbital implants with uniform pores can be prepared using embedded 3D printing technology, and surface modification obviously improves hydrophilicity and biocompatibility of the silicone implants for potential clinical application.

Indexed as

Orbital ImplantsSiliconAnimalsEndothelial CellsPorosityPrinting, Three-DimensionalRatsSiliconesSwineSiliconSiliconescollagenembedded 3D printingorbital implantpolydopaminesilicone

Identifiers

PMID37313820
PMCPMC10267231
OpenAlexW4380577261

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.