Evidence map›Paper›PMID 37313812›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2023

[Activation of GABAergic neurons in the zona incerta accelerates anesthesia induction with sevoflurane and propofol without affecting anesthesia maintenance or awakening in mice].

F Cao, Y Guo, S Guo, Z Zhou, J Cao, L Tong, W Mi

Open access · greenAbstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

F CaoDepartment of Anesthesia, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
Y GuoDepartment of Anesthesia, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
S GuoDepartment of Anesthesia, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
Z ZhouDepartment of Anesthesia, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
J CaoDepartment of Anesthesia, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
L TongDepartment of Anesthesia, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
W MiDepartment of Anesthesia, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
Chinese PLA General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the regulatory effects of GABAergic neurons in the zona incerta (ZI) on sevoflurane and propofol anesthesia.

methodsForty-eight male C57BL/6J mice divided into 8 groups (

resultsIn sevoflurane anesthesia, the induction time of anesthesia was significantly shorter in hM3Dq group than in mCherry group (

conclusionActivation of the GABAergic neurons in the ZI promotes anesthesia induction of sevoflurane and propofol but does not affect anesthesia maintenance or awakening.

Indexed as

PropofolZona IncertaAnesthesia, GeneralAnimalsGABAergic NeuronsMaleMiceMice, Inbred C57BLSevofluranePropofolSevofluraneGABAergic neuronsgamma-aminobutyric acidpropofolsevofluranezone incerta

Identifiers

PMID37313812
PMCPMC10267229
OpenAlexW4380576963

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.