Evidence map›Paper›PMID 37313720›Full record

ArticleEpidemiology and infection2022

Association of patient characteristics with clinical outcomes in a cohort of hospitalised patients with SARS-CoV-2 infection in a Greek referral centre for COVID-19.

I Rapti, A Asimakopoulos, A Liontos, M Kosmidou, E Christaki, D Biros, O Milionis, S Tsourlos, E Ntotsikas, E Ntzani and 6 more

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Article in Epidemiology and infection, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

I RaptiDepartment of Internal Medicine, Ioannina University Hospital, University of Ioannina, Ioannina, Greece.ORCID 0000-0003-1735-5839
A AsimakopoulosClinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece.
A LiontosDepartment of Internal Medicine, Ioannina University Hospital, University of Ioannina, Ioannina, Greece.
M KosmidouDepartment of Internal Medicine, Ioannina University Hospital, University of Ioannina, Ioannina, Greece.
E ChristakiDepartment of Internal Medicine, Ioannina University Hospital, University of Ioannina, Ioannina, Greece.
D BirosDepartment of Internal Medicine, Ioannina University Hospital, University of Ioannina, Ioannina, Greece.
O MilionisDepartment of Internal Medicine, Ioannina University Hospital, University of Ioannina, Ioannina, Greece.
S TsourlosDepartment of Internal Medicine, Ioannina University Hospital, University of Ioannina, Ioannina, Greece.
E NtotsikasClinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece.
E NtzaniClinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece.
E EvangelouClinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece.
K GartzonikaMicrobiology Department, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina 45110, Greece.
I GeorgiouGenetics and IVF Unit, Department of Obstetrics and Gynaecology, Medical School, University of Ioannina, Ioannina 45110, Greece.
I TzoulakiClinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece.
K TsilidisClinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece.
H MilionisDepartment of Internal Medicine, Ioannina University Hospital, University of Ioannina, Ioannina, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patient-important outcomes related to coronavirus disease 2019 (COVID-19) continue to drive the pandemic response across the globe. Various prognostic factors for COVID-19 severity have emerged and their replication across different clinical settings providing health services is ongoing. We aimed to describe the clinical characteristics and their association with outcomes in patients hospitalised with COVID-19 in the University Hospital of Ioannina. We assessed a cohort of 681 consecutively hospitalised patients with COVID-19 from January 2020 to December 2021. Demographic data, underlying comorbidities, clinical presentation, biochemical markers, radiologic findings, COVID-19 treatment and outcome data were collected at the first day of hospitalisation and up to 90 days. Multivariable Cox regression analyses were performed to investigate the associations between clinical characteristics (hazard ratios (HRs) per standard deviation (s.d.)) with intubation and/or mortality status. The participants' mean age was 62.8 (s.d., 16.9) years and 57% were males. The most common comorbidities were hypertension (45%), cardiovascular disease (19%) and diabetes mellitus (21%). Patients usually presented with fever (81%), cough (50%) and dyspnoea (27%), while lymphopenia and increased inflammatory markers were the most common laboratory abnormalities. Overall, 55 patients (8%) were intubated, and 86 patients (13%) died. There were statistically significant positive associations between intubation or death with age (HR: 2.59; 95% CI 1.52-4.40), lactate dehydrogenase (HR: 1.44; 95% CI 1.04-1.98), pO

Indexed as

COVID-19COVID-19 Drug TreatmentInpatientsAgedComorbidityFemaleGreeceHospital MortalityHumansMaleMiddle AgedRisk FactorsSARS-CoV-2COVID-19hospitalisationintubationmortalityrisk factors

Identifiers

PMID37313720
PMCPMC9464503

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.