Evidence map›Paper›PMID 37313651›Full record

ArticleLab on a chip2023

Acrylic-based culture plate format perfusion device to establish liver endothelial-epithelial interface.

Dennis McDuffie, Charles G Alver, Bhumi Suthar, Madeline Helm, David Oliver, R Alan Burgess, David Barr, Emmanuel Thomas, Ashutosh Agarwal

Abstract read
In one paragraph

Article in Lab on a chip, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Targeted Cancer Therapy-on-A-Chip.Advanced healthcare materials · 2024
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dennis McDuffieDepartment of Biomedical Engineering, University of Miami, Coral Gables, FL, USA. A.agarwal2@miami.edu.
Charles G AlverDepartment of Biomedical Engineering, University of Miami, Coral Gables, FL, USA. A.agarwal2@miami.edu.
Bhumi SutharDepartment of Biomedical Engineering, University of Miami, Coral Gables, FL, USA. A.agarwal2@miami.edu.
Madeline HelmDepartment of Biomedical Engineering, University of Miami, Coral Gables, FL, USA. A.agarwal2@miami.edu.
David OliverDepartment of Biomedical Engineering, University of Miami, Coral Gables, FL, USA. A.agarwal2@miami.edu.
R Alan BurgessDepartment of Pathology & Laboratory Medicine, Schiff Center for Liver Diseases, University of Miami Miller School of Medicine, Miami, FL, USA. Ethomas1@med.miami.edu.
David BarrDepartment of Pathology & Laboratory Medicine, Schiff Center for Liver Diseases, University of Miami Miller School of Medicine, Miami, FL, USA. Ethomas1@med.miami.edu.
Emmanuel ThomasDepartment of Pathology & Laboratory Medicine, Schiff Center for Liver Diseases, University of Miami Miller School of Medicine, Miami, FL, USA. Ethomas1@med.miami.edu.
Ashutosh AgarwalDepartment of Biomedical Engineering, University of Miami, Coral Gables, FL, USA. A.agarwal2@miami.edu.ORCID 0000-0002-2397-9886

Funding

Tumor Biology Research ProgramP30CA240139 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Stephen D. Nimer · 2019 to 2026
$24.1M
A MULTIFACETED APPROACH TO STUDY TISSUE AND CELL TYPE SPECIFIC MOLECULAR MECHANISMS OF THE HOST RESPONSE TO ACUTE/CHRONIC VIRAL INFECTIONR35GM124915 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Emmanuel Thomas · 2017 to 2026
$3.9M
Engineering a Human Microphysiological System for the Characterization of Islet-Immune InteractionsUH3DK122638 · NIDDK · UNIVERSITY OF FLORIDA · PI AGARWAL, ASHUTOSH, BRUSKO, TODD MICHAEL · 2021 to 2023
$3.0M
Defining a Role for Liver Myeloid Cells in Viral Persistence under ART-SUPPLEMENT 1R01DK131533 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Mario Stevenson, Emmanuel Thomas · 2022 to 2026
$2.5M
Human Liver Tissue & Hepatocytes Research Resource (HLTHRR)R24DK139775 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DAVID A GELLER, Satdarshan Singh Monga · 2024 to 2026
$1.4M
Glomerulus on a Chip: A Model to Study Glomerular HyperfiltrationF31DK132916 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ALVER, CHARLES GARCIA · 2022 to 2024
$158k
NCI NIH HHS P30 CA240139NIDDK NIH HHS F31 DK132916NIDDK NIH HHS R01 DK131533NIDDK NIH HHS R24 DK139775NIDDK NIH HHS UH3 DK122638NIGMS NIH HHS R35 GM124915
6 · The paper itself

Abstract

Microphysiological Systems (MPSs) or organs-on-chips, are microfluidic devices used to model human physiology

Indexed as

HepatocytesLiverHumansHuman Umbilical Vein Endothelial CellsLab-On-A-Chip DevicesPerfusion

Identifiers

PMID37313651
PMCPMC10351567

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.