ReviewJournal of clinical and translational science2023
Guidance on selecting a translational framework for intervention development: Optimizing interventions for impact.
Review in Journal of clinical and translational science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07609342 (Optimizing a School-Based Therapeutic Play Intervention for Preschool Students), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Optimizing a School-Based Therapeutic Play Intervention for Preschool Students: A Factorial Experiment Protocol
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Advancing translational research in digital cardiac rehabilitation: The preparation phase of the Multiphase Optimization Strategy.Translational behavioral medicine · 2025Pooled it
- Food systems and market pathways to childhood stunting in mining communities: evidence from a cross-sectional survey and a synthesis of context-responsive nutrition interventions.BMC public health · 2026Article
- Translating behavioral interventions into virtual reality: theFrontiers in digital health · 2026Article
- Development of a nurse-led, evidence-based, and theory-informed dietary intervention to modify multiple unhealthy dietary behaviors in gastric cancer survivors.Asia-Pacific journal of oncology nursing · 2025Article
- Integrating implementation science and intervention optimization.Implementation science : IS · 2025Article
- Evaluating smoking cessation interventions for people living with HIV in a factorial randomised clinical trial in South Africa using the Multiphase Optimization Strategy (MOST) framework: The Tlogela Trial protocol.Contemporary clinical trials · 2025Article
- Just-In-Time Adaptive Interventions to Promote Behavioral Health: Protocol for a Systematic Review.JMIR research protocols · 2025Article
- Preparing to implement Floreciendo with Latina teens and their female caregivers: Integrating implementation science and the multiphase optimization strategy framework.Translational behavioral medicine · 2025Article
- Twenty years of intervention optimization.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025Article
- Contextual determinates of under-five malnutrition in mining communities: a critical review of nutrition interventions for optimal impact.Frontiers in public health · 2025Article
- Leveraging Implementation Science at the Early-Stage Development of a Novel Telehealth-Delivered Fear of Exercise Program to Understand Intervention Feasibility and Implementation Potential: Feasibility Behavioral Intervention Study.JMIR formative research · 2024Article
- Replicability, adaptability and long-term impact of the 'Healthy Youngsters, Healthy Dads' program in Newcastle, Australia.Health promotion international · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Intervention development frameworks offer the behavioral sciences a systematic and rigorous empirical process to guide the translation of basic science into practice in pursuit of desirable public health and clinical outcomes. The multiple frameworks that have emerged share a goal of optimization during intervention development and can increase the likelihood of arriving at an effective and disseminable intervention. Yet, the process of optimizing an intervention differs functionally and conceptually across frameworks, creating confusion and conflicting guidance on when and how to optimize. This paper seeks to facilitate the use of translational intervention development frameworks by providing a blueprint for selecting and using a framework by considering the process of optimization as conceptualized by each. First, we operationalize optimization and contextualize its role in intervention development. Next, we provide brief overviews of three translational intervention development frameworks (ORBIT, MRC, and MOST), identifying areas of overlap and divergence thereby aligning core concepts across the frameworks to improve translation. We offer considerations and concrete use cases for investigators seeking to identify and use a framework in their intervention development research. We push forward an agenda of a norm to use and specify frameworks in behavioral science to support a more rapid translational pipeline.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.