ArticleJournal of inflammation research2023
Neutrophil-to-Lymphocyte Ratio (NLR) and Platelet-to-Lymphocyte Ratio (PLR) Can Predict Spontaneous Preterm Birth?
Article in Journal of inflammation research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neutrophil to lymphocyte ratio in urolithiasis: a systematic review.BMC urology · 2025Pooled it
- Among Five First-Trimester Complete Blood Count Inflammatory Indices, the Systemic Inflammation Response Index Rises Most Consistently with the Severity of Preterm Birth.Diagnostics (Basel, Switzerland) · 2026Article
- Article
- Neutrophil-to-lymphocyte ratio at admission helps to predict the need for blood transfusion after vaginal delivery.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- The association of inflammatory markers with cerclage failure in twin pregnancies.BMC pregnancy and childbirth · 2026Article
- Prediction of preterm and low birth weight risk using a physiology based artificial neural network integrating hematological, dental, and periodontal index markers: a cross sectional study based on machine learning.BMC pregnancy and childbirth · 2026Article
- Association of immunonutrition-based indices (Hemoglobin-Albumin-Lymphocyte-Platelet, prognostic nutritional index, and C-reactive protein-albumin-lymphocyte) with the latency period in preterm prelabor rupture of membranes.Revista da Associacao Medica Brasileira (1992) · 2026Article
- Predictive Value of Neutrophils, Lymphocytes, Platelets, Neutrophil-Lymphocyte Ratio (NLR), and Platelets-Lymphocyte Ratio (PLR) in Preterm Labor: Single and Combined Indices.Obstetrics and gynecology international · 2026Article
- Systemic inflammation indices measured shortly before delivery are not associated with preterm birth in pregnant women with endometriosis.BMC pregnancy and childbirth · 2025Article
- Neutrophil-To-Lymphocyte Ratio and Delivery Within 24 h in Preterm Premature Rupture of Membranes: A Retrospective Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Evaluating the efficacy of LDH and inflammatory indices in discriminating neonatal respiratory distress syndrome from transient tachypnea of the newborns.BMC pediatrics · 2025Article
- Predictive Value of Centered Clinical Asymmetric Lower Limb Edema in Diagnosing Deep Vein Thrombosis in Puerperium.Journal of clinical medicine · 2025Article
- Inflammatory Indices and Preterm Delivery: A New Horizon in Obstetric Risk Assessment.Diagnostics (Basel, Switzerland) · 2025Article
- The role of inflammatory indices for the prediction of preeclampsia in the first trimester: a case-control study from a tertiary center.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Divergent associations of inflammatory markers with bone turnover markers in elderly patients with osteoporotic fractures.Scientific reports · 2024Article
- Correlation between Maternal Systemic Inflammatory Indicators before Delivery and Congenital Pneumonia in Newborns: A Case-Control Study.Children (Basel, Switzerland) · 2024Article
- Longitudinal Cervical Length Measurements and Spontaneous Preterm Birth in Singleton and Twin Pregnancies.JAMA network open · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To investigate the role of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in the prediction of spontaneous preterm birth. Patients and Methods: Data was retrospectively collected from hospital record between February 2018 and November 2022. Pregnant women (n = 78) with a single pregnancy between 24 and 34 weeks of gestation, presented with labor pain, and had regular uterine contractions (threatened preterm labor - TPL) were included. Patients delivered within the first week after TPL were included in group 1 (n = 40) and who delivered after in group 2 (n = 38). Two groups were investigated for NLR and PLR values. Results: The median cervical length among women who gave birth within a week was significantly lower (24.5 versus 30.0 p < 0.001). The median neutrophil-to-lymphocyte ratio among women who gave birth within a week was significantly higher (6.4 versus 4.5 p < 0.001). The median platelet-to-lymphocyte ratio among women who gave birth within a week was significantly higher (151 versus 131 p < 0.001). The cut-off values to predict preterm birth were >5 for NLR (sensitivity: 90%, specificity: 92.1%), >139 for PLR (sensitivity: 97.5%, specificity: 100%). Conclusion: NLR and PLR values predict spontaneous preterm birth with high sensitivity and specificity. By predicting preterm birth, the pregnancy process can be managed sensitively and smoothly.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.