ReviewJournal of dental anesthesia and pain medicine2023
Ketamine-propofol (ketofol) in procedural sedation: a narrative review.
Review in Journal of dental anesthesia and pain medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Role of Propofol in Alcohol Withdrawal Syndrome: A Systematic Review.Journal of clinical pharmacology · 2025Pooled it
- Effect of Different Doses of Esketamine on the Propofol Effect-Site Concentration Required to Suppress Cervical Dilation-Associated Movement During Hysteroscopy: A Prospective, Randomised, Controlled, Parallel-Group Dose-Response Trial.Drug design, development and therapy · 2026Trial
- Predictors of hemodynamic instability during ERCP sedation in older adults: impact of sedation strategy in a retrospective cohort.BMC geriatrics · 2026Article
- A physiology-guided ketofol-based anaesthetic approach for emergency burr hole craniotomy in a child with Eisenmenger syndrome: a case report.BMC anesthesiology · 2026Article
- Nationwide trends in intravenous sedative and analgesic drug use in Korean dental institutions: a big data analysis using the Narcotics Information Management System from 2020 to 2024.Journal of dental anesthesia and pain medicine · 2026Article
- Anaesthetic Adverse Events During Propofol-Based Sedation for ERCP: A Real-World Cohort Study.Journal of clinical medicine · 2026Article
- A Prospective Comparative Non-randomized Study of Ketofol Versus Midazolam Sedation in Flexible Bronchoscopy.Cureus · 2026Article
- Impact of Opioid-Free Anesthesia Combined With Enhanced Recovery After Surgery Protocol on Postoperative Recovery Quality in Patients Undergoing Laparoscopic Total Hysterectomy.The journal of obstetrics and gynaecology research · 2026Article
- A Comparative Evaluation of Midazolam, Ketamine and Their Combination as Sedative Agents in Pediatric Dentistry: A Systematic Review and Meta-analysis.Frontiers in dentistry · 2025Review
- Effect of a single dose of sufentanil as an adjunct to ketofol-based monitored anesthesia care for ambulatory surgery: A retrospective case-control study.Saudi journal of anaesthesiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sedation methods for dental treatment are increasingly explored. Recently, ketofol, which is a combination of ketamine and propofol, has been increasingly used because the advantages and disadvantages of propofol and ketamine complement each other and increase their effectiveness. In this review, we discuss the pharmacology of ketamine and propofol, use of ketofol in various clinical situations, and differences in efficacy between ketofol and other sedatives.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.