Evidence map›Paper›PMID 37313191›Full record

ArticleArchives of medical science : AMS2023

Prognostic value of TIMM50 expression in colorectal cancer.

Bo Sun, Jun Wang, Yan-Feng Zhu, Zhen-Yang Li, Jian-Bin Xiang, Zong-You Chen, Zhi-Gang He, Xiao-Dong Gu

Abstract read
In one paragraph

Article in Archives of medical science : AMS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bo SunDepartment of Gastric Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Jun WangDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Yan-Feng ZhuDepartment of Nursing, Huashan Hospital, Fudan University, Shanghai, China.
Zhen-Yang LiDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Jian-Bin XiangDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Zong-You ChenDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Zhi-Gang HeDepartment of General Surgery, Shanghai Songjiang District Central Hospital, Shanghai, China.
Xiao-Dong GuDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Translocase of the inner mitochondrial membrane 50 (TIMM50) is universally considered to play a key role in several malignancies. However, its role in predicting colorectal cancer (CRC) patient prognosis remains unclear. Material and methods: A total of 192 CRC patients (123 men and 69 women) who underwent radical resection participated in this study. The patients were followed up every 3 months after surgery for 5 years. TIMM50 expression in tumour tissues was measured by quantitative real-time PCR, Western blotting and immunohistochemistry. TIMM50 expression was studied to assess correlations with clinicopathological factors and survival time. Results: TIMM50 expression increased significantly in CRC tumour tissues. Moreover, high TIMM50 expression was related to pathologic stage ( Conclusions: TIMM50 may be a key factor for monitoring CRC and a new prognosis indicator for CRC patients.

Indexed as

colorectal cancerprognosissurvivaltranslocase of the inner mitochondrial membrane 50

Identifiers

PMID37313191
PMCPMC10259394

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.