Evidence map›Paper›PMID 37313075›Full record

ReviewCureus2023

Air Pollution and Its Adverse Effects on the Central Nervous System.

Ameerah Ruzeeq Alhussaini, Meaad Refaay Aljabri, Zeyad T Al-Harbi, Gadah Abdulrahman Almohammadi, Talal M Al-Harbi, Shahid Bashir

Abstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Estimating PMToxics · 2025
    Article
  7. Review
  8. Review
  9. Article
  10. Foreign Contaminants Target Brain Health.CNS & neurological disorders drug targets · 2025
    Review
  11. Greater exposure to PMEnvironmental health : a global access science source · 2024
    Observational
  12. Effects of Composite Air Pollution and Genetic Susceptibility on Tinnitus Risk: A Large Population-Based Study.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ameerah Ruzeeq AlhussainiCollege of Medicine, Taibah University, Madinah, SAU.
Meaad Refaay AljabriCollege of Medicine, Taibah University, Madinah, SAU.
Zeyad T Al-HarbiCollege of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, SAU.
Gadah Abdulrahman AlmohammadiCollege of Medicine, Taibah University, Madinah, SAU.
Talal M Al-HarbiNeurology, King Fahad Specialist Hospital, Dammam, SAU.
Shahid BashirNeuroscience, Neuroscience Center, King Fahad Specialist Hospital, Dammam, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Air pollution is recognized as a significant public health problem and is associated with illnesses of the central nervous system (CNS) as well as neuroinflammation and neuropathology. Air pollution may cause chronic brain inflammation, white matter abnormalities, and microglia activation, which increases the risk of autism spectrum disorders, neurodegenerative disorders, stroke, and multiple sclerosis (MS). Methods: A literature review was done on "PubMed, EMBASE and Web of Science" on the relationship of air pollution with MS and stroke, using the keywords "air pollution" OR "pollution"; "ambient air pollution," "particulate matter, ozone, black carbon" AND "stroke" OR "cerebrovascular diseases," "multiple sclerosis," "neuroinflammation," or "neurodegeneration." Results: We first identified 128 articles and their related websites, of which 44 articles were further selected for analysis mainly based on study relevance, study quality and reliability, and date of publication. Further studies on air pollution and its adverse effects on the CNS are needed. The findings of such studies will support the development of appropriate preventive measures in the future.

Indexed as

air pollutioncentral nervous system disorderneuroinflammationneuropathologystroke

Identifiers

PMID37313075
PMCPMC10259194

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.