Evidence map›Paper›PMID 37312935›Full record

ReviewInternational journal of nanomedicine2023

Combat Against Gynecological Cancers with Blood Vessels as Entry Point: Anti-Angiogenic Drugs, Clinical Trials and Pre-Clinical Nano-Delivery Platforms.

Shan Yang, Weidong Fei, Yunchun Zhao, Fengmei Wang, Yiqing Ye, Fenfen Wang

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shan YangDepartment of Pharmacy, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, Peoples Republic of China.
Weidong FeiDepartment of Pharmacy, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, Peoples Republic of China.
Yunchun ZhaoDepartment of Pharmacy, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, Peoples Republic of China.
Fengmei WangDepartment of Pharmacy, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, Peoples Republic of China.
Yiqing YeDepartment of Pharmacy, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, Peoples Republic of China.
Fenfen WangDepartment of Gynecology Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, Peoples Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiogenesis is an essential mechanism for the progression of gynecological cancers. Although approved anti-angiogenic drugs have demonstrated clinical efficacy in treating gynecological cancers, the full potential of therapeutic strategies based on tumor blood vessels has not yet been realized. This review summarizes the latest angiogenesis mechanisms involved in the progression of gynecological cancers and discusses the current clinical practice of approved anti-angiogenic drugs and related clinical trials. Given the close relationship between gynecological cancers and blood vessels, we highlight more delicate strategies for regulating tumor vessels, including wise drug combinations and smart nano-delivery platforms to achieve highly efficient drug delivery and overall vessel microenvironment regulation. We also address current challenges and future opportunities in this field. We aim to generate interest in therapeutic strategies that target blood vessels as a key entry point and offer new potential and inspiration for combating gynecological cancers.

Indexed as

Angiogenesis InhibitorsNeoplasmsDrug Delivery SystemsHumansTumor MicroenvironmentAngiogenesis Inhibitorsanti-angiogenicclinical trialsgynecological cancersnano-delivery platformsnanoparticlestumor blood vesseltumor vascularization

Identifiers

PMID37312935
PMCPMC10259534

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.