Evidence map›Paper›PMID 37312917›Full record

ArticlePostepy dermatologii i alergologii2023

Shift in skin microbiota of children with atopic dermatitis after topical gentian violet application.

Joanna Krzysiek, Joanna Żurawska-Olszewska, Izabela Szczerba, Aleksandra Lesiak, Dorota Pastuszak-Lewandoska, Janina Grzegorczyk, Magdalena Ciążyńska, Joanna Narbutt

Abstract read
In one paragraph

Article in Postepy dermatologii i alergologii, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joanna KrzysiekDepartment of Dermatology, Pediatric and Oncology Dermatology, Medical University of Lodz, Lodz, Poland.
Joanna Żurawska-OlszewskaMicrobiology and Laboratory Medical Immunology, Medical University of Lodz, Lodz, Poland.
Izabela SzczerbaMicrobiology and Laboratory Medical Immunology, Medical University of Lodz, Lodz, Poland.
Aleksandra LesiakDepartment of Dermatology, Pediatric and Oncology Dermatology, Medical University of Lodz, Lodz, Poland.
Dorota Pastuszak-LewandoskaMicrobiology and Laboratory Medical Immunology, Medical University of Lodz, Lodz, Poland.
Janina GrzegorczykMicrobiology and Laboratory Medical Immunology, Medical University of Lodz, Lodz, Poland.
Magdalena CiążyńskaDepartment of Dermatology, Pediatric and Oncology Dermatology, Medical University of Lodz, Lodz, Poland.
Joanna NarbuttDepartment of Dermatology, Pediatric and Oncology Dermatology, Medical University of Lodz, Lodz, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Increasing usage of antimicrobial agents may contribute to bacterial resistance in atopic dermatitis (AD). In this case an alternative topical treatment might be gentian violet (GV), suggested for its antibacterial and antifungal properties. Aim: To assess the microbial composition of lesional skin in children with AD and a control group aged 2-12 years, before and after 3 days of 2% aqueous GV application. Material and methods: Skin samples were taken from 30 AD patients and 30 healthy controls aged 2-12 years. The procedure was done two times - before and after 3 days of 2% aqueous GV application. The material was collected from skin lesions in the cubital fossa using 25 cm Results: The results revealed a statistically significant reduction in total counts of bacteria in both groups of children after GV application ( Conclusions: Our study results show that GV does not damage the skin surface ecosystem and allows the reduction of excessive bacterial counts on eczematous lesions to a 'safe' level, similar to that of healthy children.

Indexed as

atopic dermatitisgentian violetmicrobiome

Identifiers

PMID37312917
PMCPMC10258698

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.