SynthesisJournal of orthopaedic surgery and research2023
Regional versus general anesthesia in older patients for hip fracture surgery: a systematic review and meta-analysis of randomized controlled trials.
Synthesis in Journal of orthopaedic surgery and research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Impact of Loco-regional Anaesthetic Techniques Versus General Anaesthesia in Women Aged ≥ 65 Undergoing Primary Breast Cancer Surgery: A Systematic Review of the Literature.Advances in therapy · 2026Pooled it
- Regional versus general anesthesia for femur and hip fracture surgery: A meta-analysis of postoperative outcomes and complications.The Journal of international medical research · 2026Pooled it
- Management and optimisation in the preoperative phase for patients with a fractured hip.EFORT open reviews · 2026Review
- A Machine Learning-Based Clinical Decision Support Tool for Intertrochanteric Hip Fracture Patients to Predict Postoperative Anemia Risk: A Retrospective Cohort Study.Bioengineering (Basel, Switzerland) · 2026Article
- A multidisciplinary comfort-enhanced recovery after surgery program improves perioperative patient-reported outcomes after lung cancer surgery: a randomized controlled trial.Journal of thoracic disease · 2026Article
- General Anesthesia in Psychiatric Patients Undergoing Orthopedic Surgery: A Mechanistic Narrative Review-Reports (MDPI) · 2025Review
- A clinical prediction model for postoperative delirium following surgical treatment of femoral fractures in older adult patients: development and validation study.BMC anesthesiology · 2025Article
- Review
- Review
- Association of anaesthesia type with one-year mortality after surgery in elderly patients: a secondary retrospective cohort study.BMC anesthesiology · 2025Article
- A modified approach of combined anterior lumbar plexus block with lateral sacral plexus block in a semi lateral supine position for lower limb fracture patients: a case series.BMC anesthesiology · 2025Article
- Precision and safety advantages of ultrasound-guided nerve blocks in geriatric anesthesia: current status and future prospects.Frontiers in medicine · 2025Article
- Patients risk for mortality at 90 days after proximal femur fracture - a retrospective study in a tertiary care hospital.BMC geriatrics · 2024Article
- Effects of general and spinal anesthesia on postoperative rehabilitation in older adults after lower limb surgery: a retrospective cohort study.Frontiers in medicine · 2024Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe optimal anesthesia technique for older patients undergoing hip fracture surgery remains controversial. We performed a systematic review and meta-analysis of updated randomized controlled trials (RCTs) to assess whether regional anesthesia was superior to general anesthesia in hip fracture surgery.
methodsWe searched PubMed, EMBASE, Web of Science, and the Cochrane Central Register of Controlled Trials from January 2000 until April 2022. RCTs directly comparing regional and general anesthesia in hip fracture surgery were included in the analysis. The incidence of delirium and mortality were the primary outcomes and other perioperative outcomes including complications were secondary outcomes.
resultsThirteen studies involving 3736 patients were included in this study. There was no significant difference in the incidence of delirium (odds ratio [OR] 1.09; 95% confidence interval [CI] 0.86, 1.37) and mortality (OR 1.08; 95% CI 0.71, 1.64) between the two groups. Patients receiving regional anesthesia in hip fracture surgery were associated with a reduction in operative time (weighted mean difference [WMD]: - 4.74; 95% CI - 8.85, - 0.63), intraoperative blood loss (WMD: - 0.25; 95% CI - 0.37, - 0.12), postoperative pain score (WMD: - 1.77; 95% CI - 2.79, - 0.74), length of stay (WMD: - 0.10; 95% CI - 0.18, - 0.02), and risk of acute kidney injury (AKI) (OR 0.56; 95% CI 0.36, 0.87). No significant difference was observed in the other perioperative outcomes.
conclusionsFor older patients undergoing hip fracture surgery, RA did not significantly reduce the incidence of postoperative delirium and mortality compared to GA. Due to the limitations of this study, the evidence on delirium and mortality was still inconclusive and further high-quality studies are needed.
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Registered trials
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