Evidence map›Paper›PMID 37312001›Full record

ArticleJournal of cancer survivorship : research and practice2024

Prevalence and factors associated with cancer-related fatigue in Swiss adult survivors of childhood cancer.

Tomáš Sláma, Fabiën N Belle, Sven Strebel, Salome Christen, Eva Hägler-Laube, Jochen Rössler, Claudia E Kuehni, Nicolas X von der Weid, Christina Schindera

Open access · hybridAbstract read
In one paragraph

Article in Journal of cancer survivorship : research and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Cohort Profile Update: The Swiss Childhood Cancer Survivor Cohort.International journal of epidemiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Tomáš SlámaChildhood Cancer Research Group, Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0002-4422-479X
Fabiën N BelleChildhood Cancer Research Group, Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0002-0037-4817
Sven StrebelChildhood Cancer Research Group, Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0002-0576-4865
Salome ChristenDepartment of Health Sciences and Medicine, University of Lucerne, Lucerne, Switzerland.ORCID http://orcid.org/0000-0002-3831-4350
Eva Hägler-LaubeDepartment of Internal Medicine, Cantonal Hospital Baden, Baden, Switzerland.ORCID http://orcid.org/0000-0003-0745-5035
Jochen RösslerPediatric Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0003-4022-4917
Claudia E KuehniChildhood Cancer Research Group, Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0001-8957-2002
Nicolas X von der WeidDivision of Pediatric Oncology/Hematology, University Children's Hospital Basel, University of Basel, Basel, Switzerland.ORCID http://orcid.org/0000-0002-9555-3817
Christina SchinderaChildhood Cancer Research Group, Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland. christina.schindera@unibe.ch.ORCID http://orcid.org/0000-0002-4511-287X
University of Bern · CHKantonsspital Baden · CHUniversity of Basel · CHUniversity of Geneva · CHUniversity of Lucerne · CH

Funding

CANSEARCH Foundation HSR-4951-11-2019Krebsliga Schweiz KLS/KFS-4825-01-2019Swiss Cancer Research Foundation KFS-4722-02-2019Swiss Cancer Research Foundation KFS-5027-02-2020
6 · The paper itself

Abstract

purposeReported prevalence of cancer-related fatigue (CRF) among childhood cancer survivors (CCS) varies widely, and evidence on factors associated with CRF among CCS is limited. We aimed to investigate the prevalence of CRF and its associated factors among adult CCS in Switzerland.

methodsIn a prospective cohort study, we invited adult CCS who survived at least 5 years since last cancer diagnosis, and were diagnosed when age 0-20 years and treated at Inselspital Bern between 1976 and 2015 to complete two fatigue-measuring instruments: the Checklist Individual Strength subjective fatigue subscale (CIS8R; increased fatigue 27-34, severe fatigue ≥ 35) and the numerical rating scale (NRS; moderate fatigue 4-6, severe fatigue 7-10). We collected information about previous cancer treatment and medical history, and calculated β coefficients for the association between CIS8R/NRS fatigue scores and potential determinants using multivariable linear regression.

resultsWe included 158 CCS (participation rate: 30%) with a median age at study of 33 years (interquartile range 26-38). Based on CIS8R, 19% (N = 30) of CCS reported increased fatigue, yet none reported severe fatigue. CRF was associated with female sex, central nervous system (CNS) tumors, sleep disturbance, and endocrine disorders. Lower CRF levels were observed among CCS age 30-39 years compared to those younger.

conclusionsA considerable proportion of adult CCS reported increased levels of CRF. IMPLICATIONS FOR CANCER SURVIVORS: CCS who are female and < 30 years old, have a history of CNS tumor, report sleep disturbance, or have an endocrine disorder should be screened for CRF.

Indexed as

Cancer SurvivorsNeoplasmsAdolescentAdultChildChild, PreschoolFatigueFemaleHumansInfantInfant, NewbornMalePrevalenceProspective StudiesSwitzerlandYoung AdultChildhood cancerFatigueLate effectsQuestionnairesSurvivors

Identifiers

PMID37312001
PMCPMC10866786
OpenAlexW4380537742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.