ArticleEuropean radiology2023
Photon-counting CT for diagnosis of acute pulmonary embolism: potential for contrast medium and radiation dose reduction.
Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
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Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The application of infrared thermography technology in flap: A perspective from bibliometric and visual analysis.International wound journal · 2023Pooled it
- Deep learning reconstruction combined with contrast-enhancement boost in dual-low dose CT pulmonary angiography: a two-center prospective trial.European radiology · 2025Trial
- A randomised controlled trial comparing three clinical administration strategies in spectral detector CT pulmonary angiography with low contrast medium dose.European radiology · 2025Trial
- Clinical application of third-generation dual-source CT-based dynamic imaging reconstruction for pulmonary embolism imaging.Journal of cardiothoracic surgery · 2025Trial
- Increasing pulmonary artery visibility and diagnostic confidence with ultra-high resolution photon-counting detector CT pulmonary angiography.European radiology · 2026Article
- Photon counting detector CT contrast agent-reduced transcatheter aortic valve reconstruction planning: a comparative study.European radiology · 2026Article
- Feasibility of reducing radiation dose and contrast dose while improving image quality in dual-energy CT pulmonary angiography : Use of low-energy virtual monochromatic images with deep learning image reconstruction algorithm.Radiologie (Heidelberg, Germany) · 2026Article
- Photon-counting detector CT for CT pulmonary angiography: a systematic review and meta-analysis.European radiology · 2026Article
- A Practical Rule-of-Thumb to Adapt Contrast Media Dose in Photon-counting Detector CT: The 10-to-5 Rule.Investigative radiology · 2026Article
- ERS Congress 2025: highlights from the Pulmonary Vascular Diseases Assembly.ERJ open research · 2026Article
- Photon-counting detector computed tomography in thoracic oncology: revolutionizing tumor imaging through precision and detail.Diagnostic and interventional radiology (Ankara, Turkey) · 2026Review
- Differentiation of tumor budding grade in colon cancer using noise-optimized virtual monoenergetic image in dual-energy CT.Abdominal radiology (New York) · 2026Article
- Dual-energy CT pulmonary angiography using dual-flow mixture bolus tracking: potential for contrast medium and radiation exposure reduction.Insights into imaging · 2026Article
- Quantitative imaging of the central lymphatic system with spectral CT iodine mapping: a feasibility study in swine.medRxiv : the preprint server for health sciences · 2026Article
- Optimizing CT pulmonary angiography with patient-adaptive triggering-a novel approach for a "one-stop-shop" evaluation of pulmonary and aortic vasculature.European radiology · 2026Article
- Clinical benefits and current challenges of photon-counting detector CT in vascular imaging.Radiology advances · 2026Review
- Reducing contrast media dosage for pulmonary embolism CTPA in PCD-CT: a comparative study of EID-CT and PCD-CT in the era of individualized protocolling.European radiology · 2026Article
- Photon-Counting CT Enables Higher Image Quality at a Lower Radiation Dose Compared with a 256-Slice Energy-Integrating Detector CT in Pediatric Patients with Congenital Heart Disease.Diagnostics (Basel, Switzerland) · 2026Article
- ERS Congress 2025: highlights from the Clinical Techniques, Imaging and Endoscopy Assembly.ERJ open research · 2026Article
- Impact of low-energy virtual monoenergetic imaging in photon-counting CT for pre-TAVI pelvic arteries visualization.La Radiologia medica · 2026Article
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Authors and funding
9 authors.
Funding
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Abstract
objectiveTo evaluate the image quality of an ultra-low contrast medium and radiation dose CT pulmonary angiography (CTPA) protocol for the diagnosis of acute pulmonary embolism using a clinical photon-counting detector (PCD) CT system and compare its performance to a dual-energy-(DE)-CTPA protocol on a conventional energy-integrating detector (EID) CT system.
methodsSixty-four patients either underwent CTPA with the novel scan protocol on the PCD-CT scanner (32 patients, 25 mL, CTDI
resultsSubjective image quality was deemed superior by all four reviewers for 60-keV PCD scans (excellent or good ratings in 93.8% of PCD vs. 84.4% of 60 keV EID scans, ICC = 0.72). No examinations on either system were considered "non-diagnostic." Objective image quality parameters were significantly higher in the EID group (mostly p < 0.001), both in the polychromatic reconstructions and at 60 keV. The ED (1.4 vs. 3.3 mSv) was significantly lower in the PCD cohort (p < 0.001).
conclusionsPCD-CTPA allows for considerable reduction of contrast medium and radiation dose in the diagnosis of acute pulmonary embolism, while maintaining good to excellent image quality compared to conventional EID-CTPA. CLINICAL RELEVANCE STATEMENT: Clinical PCD-CT allows for spectral assessment of pulmonary vasculature with high scan speed, which is beneficial in patients with suspected pulmonary embolism, frequently presenting with dyspnea. Simultaneously PCD-CT enables substantial reduction of contrast medium and radiation dose. KEY POINTS: • The clinical photon-counting detector CT scanner used in this study allows for high-pitch multi-energy acquisitions. • Photon-counting computed tomography allows for considerable reduction of contrast medium and radiation dose in the diagnosis of acute pulmonary embolism. • Subjective image quality was rated best for 60-keV photon-counting scans.
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