Evidence map›Paper›PMID 37311799›Full record

ArticleHuman genome variation2023

Genome-wide association study of preterm birth and gestational age in a Japanese population.

Keita Hasegawa, Natsuhiko Kumasaka, Kazuhiko Nakabayashi, Hiromi Kamura, Kayoko Maehara, Yoshifumi Kasuga, Kenichiro Hata, Mamoru Tanaka

Open access · goldAbstract read
In one paragraph

Article in Human genome variation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Keita HasegawaDepartment of Maternal-Fetal Biology, National Center for Child Health and Development, Setagaya, Tokyo, 157-8535, Japan.ORCID http://orcid.org/0000-0002-4069-8824
Natsuhiko KumasakaMedical Research Center for Japan Environment and Children's Study, National Center for Child Health and Development, Setagaya, Tokyo, 157-8535, Japan. kumasaka-n@ncchd.go.jp.
Kazuhiko NakabayashiDepartment of Maternal-Fetal Biology, National Center for Child Health and Development, Setagaya, Tokyo, 157-8535, Japan.
Hiromi KamuraDepartment of Maternal-Fetal Biology, National Center for Child Health and Development, Setagaya, Tokyo, 157-8535, Japan.
Kayoko MaeharaDepartment of Maternal-Fetal Biology, National Center for Child Health and Development, Setagaya, Tokyo, 157-8535, Japan.ORCID http://orcid.org/0000-0001-5573-7673
Yoshifumi KasugaDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Shinjuku, Tokyo, 160-0016, Japan.
Kenichiro HataDepartment of Maternal-Fetal Biology, National Center for Child Health and Development, Setagaya, Tokyo, 157-8535, Japan.
Mamoru TanakaDepartment of Obstetrics and Gynecology, Keio University School of Medicine, Shinjuku, Tokyo, 160-0016, Japan.
Keio University · JPNational Center For Child Health and Development · JPGunma University · JPKio University · JP

Funding

Japan Society for the Promotion of Science London (JSPS London) 21K19584MEXT | Japan Society for the Promotion of Science (JSPS) 21H02887National Center for Child Health and Development (NCCHD) NCCHD 2022A-3
6 · The paper itself

Abstract

Preterm birth (PTB), defined as the birth of a baby at <37 weeks of gestation, is known to be the main cause of neonatal morbidity and mortality. Here, we report genetic associations between preterm birth and gestational age in a Japanese population. We conducted a genome-wide association study (GWAS) of 384 cases who delivered prematurely and 644 controls and considered gestational age as a quantitative trait in 1028 Japanese women. Unfortunately, we were unable to identify any significant variants associated with PTB or gestational age using the current sample. We also examined genetic associations previously reported in European populations and identified no associations, even with the genome-wide subthreshold (p value < 10

Identifiers

PMID37311799
PMCPMC10264385
OpenAlexW4380576512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.