Evidence map›Paper›PMID 37311730›Full record

ArticleDiabetes, obesity & metabolism2023

Neighbourhood-level social deprivation and the risk of recurrent heart failure hospitalizations in type 2 diabetes.

Salil V Deo, Sadeer Al-Kindi, Issam Motairek, Yakov E Elgudin, Eiran Gorodeski, Khurram Nasir, Sanjay Rajagopalan, Mark C Petrie, Naveed Sattar

Open access · hybridAbstract read
In one paragraph

Article in Diabetes, obesity & metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Salil V DeoLouis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.ORCID 0000-0002-4729-1461
Sadeer Al-KindiSchool of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Issam MotairekHarrington Heart and Vascular Institute, University Hospitals, Cleveland, Ohio, USA.
Yakov E ElgudinLouis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.
Eiran GorodeskiSchool of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Khurram NasirHouston Methodist Heart Center, Houston, Texas, USA.
Sanjay RajagopalanSchool of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Mark C PetrieSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Naveed SattarSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.ORCID 0000-0002-1604-2593
University Hospitals of Cleveland · USHouston Methodist · USLouis Stokes Cleveland VA Medical Center · USThe Robertson Trust · GBUniversity of Glasgow · GB

Funding

ACHIEVE P3 - CHDP50MD017351 · NIMHD · WAYNE STATE UNIVERSITY · PI DAILEY, RHONDA K · 2021 to 2025
$21.1M
Diversity Suppplement (CIRCADIAN) Circadian Disruption as Mediator of Cardiometabolic Risk in Air PollutionR35ES031702 · NIEHS · CASE WESTERN RESERVE UNIVERSITY · PI Sanjay Rajagopalan · 2021 to 2026
$5.9M
Environmental Triggers of Cardiometabolic DiseaseR01ES019616 · NIEHS · UNIVERSITY OF MARYLAND BALTIMORE · PI BROOK, ROBERT DANIEL, RAJAGOPALAN, SANJAY · 2011 to 2020
$3.0M
NIEHS NIH HHS R01 ES019616NIEHS NIH HHS R35 ES031702NIMHD NIH HHS P50 MD017351
6 · The paper itself

Abstract

backgroundThe importance of type 2 diabetes mellitus (T2D) in heart failure hospitalizations (HFH) is acknowledged. As information on the prevalence and influence of social deprivation on HFH is limited, we studied this issue in a racially diverse cohort.

methodsLinking data from US Veterans with stable T2D (without prevalent HF) with a zip-code derived population-level social deprivation index (SDI), we grouped them according to increasing SDI as follows: SDI: group I: ≤20; II: 21-40; III: 41-60; IV: 61-80; and V (most deprived) 81-100. Over a 10-year follow-up period, we identified the total (first and recurrent) number of HFH episodes for each patient and calculated the age-adjusted HFH rate [per 1000 patient-years (PY)]. We analysed the incident rate ratio between SDI groups and HFH using adjusted analyses.

resultsIn 1 012 351 patients with T2D (mean age 67.5 years, 75.7% White), the cumulative incidence of first HFH was 9.4% and 14.2% in SDI groups I and V respectively. The 10-year total HFH rate was 54.8 (95% CI: 54.5, 55.2)/1000 PY. Total HFH increased incrementally from SDI group I [43.3 (95% CI: 42.4, 44.2)/1000 PY] to group V [68.6 (95% CI: 67.8, 69.9)/1000 PY]. Compared with group I, group V patients had a 53% higher relative risk of HFH. The negative association between SDI and HFH was stronger in Black patients (SDI × Race p

conclusionsSocial deprivation is associated with increased HFH in T2D with a disproportionate influence in Black patients. Strategies to reduce social disparity and equalize racial differences may help to bridge this gap.

Indexed as

Diabetes Mellitus, Type 2Heart FailureAgedHospitalizationHumansRiskSocial Deprivationheart failuresocial deprivationtype 2 diabetes

Identifiers

PMID37311730
PMCPMC10528514
OpenAlexW4380442337

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.