Evidence map›Paper›PMID 37311711›Full record

ArticleEnvironmental microbiology reports2023

Genomic adaptation of Burkholderia anthina to glyphosate uncovers a novel herbicide resistance mechanism.

Inge Schwedt, Madeline Collignon, Carolin Mittelstädt, Florian Giudici, Johanna Rapp, Janek Meißner, Hannes Link, Robert Hertel, Fabian M Commichau

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental microbiology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Inge SchwedtFG Synthetic Microbiology, Institute for Biotechnology, BTU Cottbus-Senftenberg, Senftenberg, Germany.
Madeline CollignonFG Synthetic Microbiology, Institute for Biotechnology, BTU Cottbus-Senftenberg, Senftenberg, Germany.
Carolin MittelstädtFG Synthetic Microbiology, Institute for Biotechnology, BTU Cottbus-Senftenberg, Senftenberg, Germany.
Florian GiudiciFG Synthetic Microbiology, Institute for Biotechnology, BTU Cottbus-Senftenberg, Senftenberg, Germany.
Johanna RappInterfaculty Institute for Microbiology and Infection Medicine Tübingen, University of Tübingen, Bacterial Metabolomics, Tübingen, Germany.
Janek MeißnerDepartment of General Microbiology, Institute for Microbiology and Genetics, University of Goettingen, Göttingen, Germany.
Hannes LinkInterfaculty Institute for Microbiology and Infection Medicine Tübingen, University of Tübingen, Bacterial Metabolomics, Tübingen, Germany.
Robert HertelFG Synthetic Microbiology, Institute for Biotechnology, BTU Cottbus-Senftenberg, Senftenberg, Germany.
Fabian M CommichauFG Synthetic Microbiology, Institute for Biotechnology, BTU Cottbus-Senftenberg, Senftenberg, Germany.ORCID 0000-0003-0323-7479
Brandenburg University of Technology Cottbus-Senftenberg · DEUniversity of Hohenheim · DEUniversity of Tübingen · DEUniversity of Göttingen · DE

Funding

Cluster of Excellence EXC 2124Deutsche Forschungsgemeinschaft CO 1139/2-2
6 · The paper itself

Abstract

Glyphosate (GS) specifically inhibits the 5-enolpyruvyl-shikimate-3-phosphate (EPSP) synthase that converts phosphoenolpyruvate (PEP) and shikimate-3-phosphate to EPSP in the shikimate pathway of bacteria and other organisms. The inhibition of the EPSP synthase depletes the cell of the EPSP-derived aromatic amino acids as well as of folate and quinones. A variety of mechanisms (e.g., EPSP synthase modification) has been described that confer GS resistance to bacteria. Here, we show that the Burkholderia anthina strain DSM 16086 quickly evolves GS resistance by the acquisition of mutations in the ppsR gene. ppsR codes for the pyruvate/ortho-P

Indexed as

3-Phosphoshikimate 1-CarboxyvinyltransferaseEscherichia coliBurkholderiaGenomicsGlyphosateHerbicide ResistancePhosphatesShikimic Acid3-Phosphoshikimate 1-CarboxyvinyltransferaseGlyphosatePhosphatesshikimateShikimic Acid

Identifiers

PMID37311711
PMCPMC10667639
OpenAlexW4380538211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.