Evidence map›Paper›PMID 37311538›Full record

ArticleOpen biology2023

Neuroanatomical characterization of the Nmu-Cre knock-in mice reveals an interconnected network of unique neuropeptidergic cells.

Mireia Medrano, Wissal Allaoui, Mathias Van Bulck, Sofie Thys, Leila Makrini-Maleville, Eve Seuntjens, Winnok H De Vos, Emmanuel Valjent, Bálazs Gaszner, Ann Van Eeckhaut and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Mireia MedranoCenter for Neurosciences, Department of Pharmaceutical Chemistry, Drug Analysis and Drug Information, Research Group Experimental Pharmacology, Vrije Universiteit Brussel, 1090 Brussels, Belgium.
Wissal AllaouiCenter for Neurosciences, Department of Pharmaceutical Chemistry, Drug Analysis and Drug Information, Research Group Experimental Pharmacology, Vrije Universiteit Brussel, 1090 Brussels, Belgium.
Mathias Van BulckLaboratory of Medical and Molecular Oncology, Vrije Universiteit Brussel, 1090 Brussels, Belgium.
Sofie ThysDepartment of Veterinary Sciences, Laboratory of Cell Biology and Histology and Antwerp Centre for Advanced Microscopy (ACAM), University of Antwerp, 2610 Antwerp, Belgium.
Leila Makrini-MalevilleIGF, Université de Montpellier, CNRS, Inserm, 34094 Montpellier, France.
Eve SeuntjensDepartment of Biology, Laboratory of Developmental Neurobiology, KU Leuven, 3000 Leuven, Belgium.
Winnok H De VosDepartment of Veterinary Sciences, Laboratory of Cell Biology and Histology and Antwerp Centre for Advanced Microscopy (ACAM), University of Antwerp, 2610 Antwerp, Belgium.
Emmanuel ValjentIGF, Université de Montpellier, CNRS, Inserm, 34094 Montpellier, France.
Bálazs GasznerMedical School, Research Group for Mood Disorders, Department of Anatomy and Centre for Neuroscience, University of Pécs, 7624 Pécs, Hungary.
Ann Van EeckhautCenter for Neurosciences, Department of Pharmaceutical Chemistry, Drug Analysis and Drug Information, Research Group Experimental Pharmacology, Vrije Universiteit Brussel, 1090 Brussels, Belgium.ORCID 0000-0002-1695-7398
Ilse SmoldersCenter for Neurosciences, Department of Pharmaceutical Chemistry, Drug Analysis and Drug Information, Research Group Experimental Pharmacology, Vrije Universiteit Brussel, 1090 Brussels, Belgium.
Dimitri De BundelCenter for Neurosciences, Department of Pharmaceutical Chemistry, Drug Analysis and Drug Information, Research Group Experimental Pharmacology, Vrije Universiteit Brussel, 1090 Brussels, Belgium.ORCID 0000-0002-6234-9908
Vrije Universiteit Brussel · BECentre National de la Recherche Scientifique · FRUniversity of Antwerp · BENeuroelectronics Research Flanders · BEUniversity of Pecs · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuromedin U (NMU) is an evolutionary conserved neuropeptide that has been implicated in multiple processes, such as circadian regulation, energy homeostasis, reward processing and stress coping. Although the central expression of NMU has been addressed previously, the lack of specific and sensitive tools has prevented a comprehensive characterization of NMU-expressing neurons in the brain. We have generated a knock-in mouse model constitutively expressing Cre recombinase under the

Indexed as

NeuropeptidesPeptide HormonesAnimalsDisease Models, AnimalIntegrasesMiceNeuronsCre recombinaseIntegrasesneuromedin UNeuropeptidesPeptide Hormonesknock-in mouse modelneuromedin Uneuropeptideventromedial hypothalamic nucleus

Identifiers

PMID37311538
PMCPMC10264104
OpenAlexW4380537638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.