Evidence map›Paper›PMID 37311520›Full record

ArticleJournal of substance use and addiction treatment2023

The impact of the implementation of medication for opioid use disorder and COVID-19 in a statewide correctional system on treatment engagement, postrelease continuation of care, and overdose.

Elias M Klemperer, Laura Wreschnig, Abigail Crocker, Jessica King-Mohr, Annie Ramniceanu, John R Brooklyn, Kelly R Peck, Richard A Rawson, Elizabeth A Evans

Open access · hybridAbstract read
In one paragraph

Article in Journal of substance use and addiction treatment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  8. Contingency management needs implementation science.Addiction (Abingdon, England) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Elias M KlempererUniversity of Vermont, College of Medicine, Department of Psychiatry, United States of America. Electronic address: elias.klemperer@med.uvm.edu.
Laura WreschnigVermont Agency of Human Services, United States of America.
Abigail CrockerUniversity of Vermont, College of Engineering Mathematical Sciences, Department of Mathematics and Statistics, United States of America.
Jessica King-MohrVermont Agency of Human Services, Department of Corrections, United States of America.
Annie RamniceanuVermont Agency of Human Services, Department of Corrections, United States of America.
John R BrooklynUniversity of Vermont, College of Medicine, Department of Family Medicine, United States of America.
Kelly R PeckUniversity of Vermont, College of Medicine, Department of Psychiatry, United States of America.
Richard A RawsonUniversity of Vermont, College of Medicine, Department of Psychiatry, United States of America.
Elizabeth A EvansUniversity of Massachusetts Amherst, School of Public Health & Health Sciences, United States of America.
University of Vermont · USUniversity of Massachusetts Amherst · USVermont Agency of Human Services · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Technical Assistance CoreU2CDA050097 · NIDA · GEORGE MASON UNIVERSITY · PI Faye S Taxman · 2019 to 2026
$37.0M
Vermont Center on Behavior and HealthP20GM103644 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI LANSING, AMY HUGHES · 2013 to 2022
$21.3M
Massachusetts Justice Cooperative Opioid Innovation Network (JCOIN) Research CenterUG1DA050067 · NIDA · UNIVERSITY OF MASSACHUSETTS AMHERST · PI EVANS, ELIZABETH A., FRIEDMANN, PETER D · 2019 to 2023
$10.5M
HEAL Accelerator: Leveraging Partnerships and Targeted Dissemination to Advance UptakeOT2OD034479 · OD · GEORGE MASON UNIVERSITY · PI TAXMAN, FAYE S · 2022 to 2023
$5.6M
NCATS NIH HHS UL1 TR001863NIDA NIH HHS U2C DA050097NIDA NIH HHS UG1 DA050067NIGMS NIH HHS P20 GM103644NIH HHS OT2 OD034479
6 · The paper itself

Abstract

backgroundPeople with opioid use disorder (OUD) are overrepresented in US correctional facilities and experience disproportionately high risk for overdose after release. Medications for OUD (MOUD) are highly efficacious but not available to most incarcerated individuals. In 2018, Vermont began providing MOUD for all incarcerated individuals with OUD statewide. In 2020, the COVID-19 state of emergency began. We assessed the impact of both events on MOUD utilization and treatment outcomes. METHODOLOGY: Analyses linked Vermont Department of Corrections administrative data and Medicaid claims data between 07/01/2017 and 03/31/2021. The study used logistic regression to analyze treatment engagement among all incarcerated individuals in Vermont. Multilevel modeling assessed change in clinical outcomes among release episodes that occurred among individuals with an OUD diagnosis Medicaid claim.

resultsPrescriptions for MOUD while incarcerated increased from 0.8% to 33.9% of the incarcerated population after MOUD implementation (OR = 67.4) and subsequently decreased with the onset of COVID-19 to 26.6% (OR = 0.7). After MOUD implementation, most prescriptions (63.1%) were to individuals who had not been receiving MOUD prior to incarceration, but this figure decreased to 53.9% with the onset of COVID-19 (OR = 0.7). Prescriptions for MOUD within 30 days after release increased from 33.9% of those with OUD before to 41.0% after MOUD implementation (OR = 1.4) but decreased to 35.6% with the onset of COVID-19 (OR = 0.8). Simultaneously, opioid-related nonfatal overdoses within 30 days after release decreased from 1.2% before to 0.8% after statewide MOUD implementation (OR = 0.3) but increased to 1.9% during COVID-19 (OR = 3.4). Fatal overdoses within 1 year after release decreased from 27 deaths before to ≤10 after statewide MOUD implementation and remained ≤10 during COVID-19.

conclusionsThis longitudinal evaluation demonstrated increased treatment engagement and a decrease in opioid-related overdose following implementation of MOUD in a statewide correctional system. In contrast, these improvements were somewhat attenuated with the onset of COVID-19, which was associated with decreased treatment engagement and an increase in nonfatal overdoses. Considered together, these findings demonstrate the benefits of statewide MOUD for incarcerated individuals as well as the need to identify and address barriers to continuation of care following release from incarceration in the context of COVID-19.

Indexed as

COVID-19Drug OverdoseOpiate OverdoseOpioid-Related DisordersAnalgesics, OpioidHumansUnited StatesAnalgesics, OpioidCorrectional facilitiesCOVID-19Medication for addiction treatmentMedication for opioid use disorderOverdosePrisons

Identifiers

PMID37311520
PMCPMC10257572
OpenAlexW4380267104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.