ArticleCell reports2023
VIP interneuron impairment promotes in vivo circuit dysfunction and autism-related behaviors in Dravet syndrome.
Article in Cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Vagus nerve stimulation for the therapy of Dravet syndrome: a systematic review and meta-analysis.Frontiers in neurology · 2024Pooled it
- Sex-Dependent Alterations in Behavioral Development of Mice Lacking α5-Nicotinic Acetylcholine Receptors.Journal of neuroscience research · 2026Article
- Motor Cortex VIP Interneurons Participate in Dexmedetomidine-Associated Sleep Modulation.Molecular neurobiology · 2026Article
- Chronic Stress Alters Dorsal Bed Nucleus of Stria Terminalis Synaptic Neurotransmission in a Dravet Syndrome Mouse Model.bioRxiv : the preprint server for biology · 2026Article
- Targeting notch signaling to restore neural development and behavior in mouse models of ASD.Nature communications · 2026Article
- Article
- Disorganized Inhibitory Dynamics in Hippocampal area CA1 of 22q11.2 Deletion Mutant Mice.bioRxiv : the preprint server for biology · 2026Article
- Genetic Diagnostic Yield in Autism Spectrum Disorder (ASD) and Epilepsy Phenotypes in Children with Genetically Defined ASD.Journal of autism and developmental disorders · 2025Article
- Medial septum parvalbumin-expressing inhibitory neurons are impaired in a mouse model of Dravet syndrome.Epilepsia · 2025Article
- Early and widespread cerebellar engagement during hippocampal seizures and interictal discharges.Neurobiology of disease · 2025Article
- Cell-type-specific cholinergic control of granular retrosplenial cortex with implications for angular velocity coding across brain states.Progress in neurobiology · 2025Article
- Emerging Insights into the Pathogenic Mechanisms of Dravet Syndrome.Neurochemical research · 2025Review
- Inhibition of BK channels by GABAb receptors enhances intrinsic excitability of layer 2/3 vasoactive intestinal polypeptide-expressing interneurons in mouse neocortex.The Journal of physiology · 2025Article
- Postnatal development of vasoactive intestinal polypeptide-expressing GABAergic interneurons in mouse somatosensory cortex.Acta physiologica (Oxford, England) · 2025Article
- Prenatal Valproic Acid Exposure Impairs Offspring Cognition Through Disturbing Interneuron Development.CNS neuroscience & therapeutics · 2025Article
- Stimulus-specific enhancement in mouse visual cortex requires GABA but not VIP-peptide release from VIP interneurons.Journal of neurophysiology · 2024Article
- Laminar Distribution of Cannabinoid Receptor 1 in the Prefrontal Cortex of Nonhuman Primates.Molecular neurobiology · 2024Article
- Ndnf Interneuron Excitability Is Spared in a Mouse Model of Dravet Syndrome.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Interneuronal modulations as a functional switch for cortical computations: mechanisms and implication for disease.Frontiers in cellular neuroscience · 2024Article
- Unspooling the Thread: VIP Interneurons Linked With Autism Spectrum Disorder Behaviors but Not Seizures in Dravet Syndrome.Epilepsy currentsArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Dravet syndrome (DS) is a severe neurodevelopmental disorder caused by loss-of-function variants in SCN1A, which encodes the voltage-gated sodium channel subunit Nav1.1. We recently showed that neocortical vasoactive intestinal peptide interneurons (VIP-INs) express Nav1.1 and are hypoexcitable in DS (Scn1a
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.