Evidence map›Paper›PMID 37310787›Full record

ArticleJournal of medical Internet research2023

Patient Engagement in a Multimodal Digital Phenotyping Study of Opioid Use Disorder.

Cynthia I Campbell, Ching-Hua Chen, Sara R Adams, Asma Asyyed, Ninad R Athale, Monique B Does, Saeed Hassanpour, Emily Hichborn, Melanie Jackson-Morris, Nicholas C Jacobson and 11 more

Abstract read
In one paragraph

Article in Journal of medical Internet research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
  4. Momentary mindfulness versus distraction coping messages to reduce cannabis craving among young adults: A microrandomized trial.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
    Article
  5. Article
  6. Smartphone and Wearable Device-Based Digital Phenotyping to Understand Substance use and its Syndemics.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Cynthia I CampbellDivision of Research, Kaiser Permanente Northern California, Oakland, CA, United States.ORCID 0000-0003-1019-5852
Ching-Hua ChenCenter for Computational Health, IBM Research, Yorktown Heights, NY, United States.ORCID 0000-0002-1020-0861
Sara R AdamsDivision of Research, Kaiser Permanente Northern California, Oakland, CA, United States.ORCID 0009-0005-0896-3199
Asma AsyyedAddiction Medicine and Recovery Services, The Permanente Medical Group Northern California, Oakland, CA, United States.ORCID 0000-0002-0851-0158
Ninad R AthaleAddiction Medicine and Recovery Services, The Permanente Medical Group Northern California, Vallejo, CA, United States.ORCID 0000-0003-4057-6154
Monique B DoesDivision of Research, Kaiser Permanente Northern California, Oakland, CA, United States.ORCID 0000-0002-6654-0793
Saeed HassanpourCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States.ORCID 0000-0001-9460-6414
Emily HichbornCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States.ORCID 0000-0003-2261-1315
Melanie Jackson-MorrisDivision of Research, Kaiser Permanente Northern California, Oakland, CA, United States.ORCID 0009-0007-3651-0642
Nicholas C JacobsonCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States.ORCID 0000-0002-8832-4741
Heather K JonesDivision of Research, Kaiser Permanente Northern California, Oakland, CA, United States.ORCID 0009-0008-4619-824X
David KotzDepartment of Computer Science, Dartmouth College, Hanover, NH, United States.ORCID 0000-0001-7411-2783
Chantal A Lambert-HarrisCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States.ORCID 0000-0002-5355-8206
Zhiguo LiCenter for Computational Health, IBM Research, Yorktown Heights, NY, United States.ORCID 0000-0002-3834-9801
Bethany McLemanCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States.ORCID 0000-0001-5382-7114
Varun MishraKhoury College of Computer Sciences, Northeastern University, Boston, MA, United States.ORCID 0000-0003-3891-5460
Catherine StangerCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States.ORCID 0000-0003-2221-5232
Geetha SubramaniamCenter for Clinical Trials Network, National Institute on Drug Abuse, Bethesda, MD, United States.ORCID 0000-0003-3806-4483
Weiyi WuDepartment of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States.ORCID 0000-0002-1571-5872
Christopher ZegersAddiction Medicine and Recovery Services, The Permanente Medical Group Northern California, Sacramento, CA, United States.ORCID 0009-0005-0634-2479
Lisa A MarschCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States.ORCID 0000-0001-6429-0965

Funding

Project-002UG1DA040309 · NIDA · DARTMOUTH COLLEGE · PI Lisa A. Marsch · 2015 to 2026
$37.9M
Project-002UG1DA040314 · NIDA · KAISER FOUNDATION RESEARCH INSTITUTE · PI Ingrid A Binswanger, CYNTHIA I CAMPBELL · 2015 to 2026
$34.9M
Treatment Development & Evaluation CoreP30DA029926 · NIDA · DARTMOUTH COLLEGE · PI Lisa A. Marsch · 2011 to 2026
$21.5M
NIDA NIH HHS P30 DA029926NIDA NIH HHS UG1 DA040309NIDA NIH HHS UG1 DA040314
6 · The paper itself

Abstract

backgroundMultiple digital data sources can capture moment-to-moment information to advance a robust understanding of opioid use disorder (OUD) behavior, ultimately creating a digital phenotype for each patient. This information can lead to individualized interventions to improve treatment for OUD.

objectiveThe aim is to examine patient engagement with multiple digital phenotyping methods among patients receiving buprenorphine medication for OUD.

methodsThe study enrolled 65 patients receiving buprenorphine for OUD between June 2020 and January 2021 from 4 addiction medicine programs in an integrated health care delivery system in Northern California. Ecological momentary assessment (EMA), sensor data, and social media data were collected by smartphone, smartwatch, and social media platforms over a 12-week period. Primary engagement outcomes were meeting measures of minimum phone carry (≥8 hours per day) and watch wear (≥18 hours per day) criteria, EMA response rates, social media consent rate, and data sparsity. Descriptive analyses, bivariate, and trend tests were performed.

resultsThe participants' average age was 37 years, 47% of them were female, and 71% of them were White. On average, participants met phone carrying criteria on 94% of study days, met watch wearing criteria on 74% of days, and wore the watch to sleep on 77% of days. The mean EMA response rate was 70%, declining from 83% to 56% from week 1 to week 12. Among participants with social media accounts, 88% of them consented to providing data; of them, 55% of Facebook, 54% of Instagram, and 57% of Twitter participants provided data. The amount of social media data available varied widely across participants. No differences by age, sex, race, or ethnicity were observed for any outcomes.

conclusionsTo our knowledge, this is the first study to capture these 3 digital data sources in this clinical population. Our findings demonstrate that patients receiving buprenorphine treatment for OUD had generally high engagement with multiple digital phenotyping data sources, but this was more limited for the social media data. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.3389/fpsyt.2022.871916.

Indexed as

BuprenorphineOpioid-Related DisordersEcological Momentary AssessmentEthnicityFemaleHumansMalePatient ParticipationBuprenorphinedata collectiondigital healthdigital phenotypingecological momentary assessmentEMAmedication for opioid use disorderMOUDopioidopioid use disorderOUDpassive sensingsmartphonesocial media

Identifiers

PMID37310787
PMCPMC10337375

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.