ArticlePsychological medicine2023
Developmental milestones in early childhood and genetic liability to neurodevelopmental disorders.
Article in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Genome-wide association meta-analysis of age at onset of walking in over 70,000 infants of European ancestry.Nature human behaviour · 2025Pooled it
- Neurodevelopmental traits as mechanisms linking genetic predispositions to bullying involvement.European child & adolescent psychiatry · 2026Article
- Can Psychiatric Genetics Advance Without Incorporating a Life Course Perspective?Biological psychiatry · 2026Review
- Risks of medical and developmental delays and associated factors among children from different racial and ethnic groups in Kalamazoo County of Michigan, United States.Frontiers in pediatrics · 2026Article
- Mediating the Impact of Prenatal Cannabis Exposure on Neurobehavioral Disinhibition: The Role of Delayed Developmental Milestone Attainment.Cannabis (Albuquerque, N.M.) · 2026Article
- Sex Differences in the role of Additive Genetic Variants in Autism: A Systematic Review.medRxiv : the preprint server for health sciences · 2025Article
- Systematic Review and Meta-Analysis: Phenotypic Correlates of the Autism Polygenic Score.JAACAP open · 2025Article
- Direct and indirect genetic effects on early neurodevelopmental traits.Journal of child psychology and psychiatry, and allied disciplines · 2025Article
- Genetic and Environmental Effects on Parent-Rated Adaptive Behaviour in Infancy.Developmental science · 2025Article
- The Assessment of Postural-Motor, Coordination, and Reflex Functions in Children and Adolescents with a History of Premature Verticalization and Ontogeny Disorders in Their First Year of Life.Children (Basel, Switzerland) · 2024Article
- The potential and translational application of infant genetic research.Nature genetics · 2024Review
- Structural models of genome-wide covariance identify multiple common dimensions in autism.Nature communications · 2024Article
- Centrality and interhemispheric coordination are related to different clinical/behavioral factors in attention deficit/hyperactivity disorder: a resting-state fMRI study.Brain imaging and behavior · 2022Article
- Research Review: How to interpret associations between polygenic scores, environmental risks, and phenotypes.Journal of child psychology and psychiatry, and allied disciplines · 2022Review
- Early manifestations of genetic liability for ADHD, autism and schizophrenia at ages 18 and 24 months.JCPP advances · 2022Article
- Genetic contributions to autism spectrum disorder.Psychological medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundTiming of developmental milestones, such as age at first walking, is associated with later diagnoses of neurodevelopmental disorders. However, its relationship to
methodsWe use data from a genotyped sub-set (
resultsWe found that ADHD PGS were associated with earlier walking age (
conclusionsGenetic liabilities for neurodevelopmental disorders show some specific associations with the age at which children first walk unsupported. Associations are small but robust and, in the case of autism PGS, differentiated by sex. These findings suggest that early-life motor developmental milestone attainment is associated with genetic liability to ADHD and autism in the general population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.