Evidence map›Paper›PMID 37310302›Full record

ArticlePsychological medicine2023

Prenatal maternal stress, child internalizing and externalizing symptoms, and the moderating role of parenting: findings from the Norwegian mother, father, and child cohort study.

Zahra M Clayborne, Wendy Nilsen, Fartein Ask Torvik, Kristin Gustavson, Mona Bekkhus, Stephen E Gilman, Golam M Khandaker, Deshayne B Fell, Ian Colman

Open access · greenAbstract read
In one paragraph

Article in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Zahra M ClayborneSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada.ORCID 0000-0003-2016-1015
Wendy NilsenWork Research Institute, OsloMet - Oslo Metropolitan University, Oslo, Norway.
Fartein Ask TorvikCentre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
Kristin GustavsonDepartment of Psychology, PROMENTA Research Center, University of Oslo, Oslo, Norway.
Mona BekkhusDepartment of Psychology, PROMENTA Research Center, University of Oslo, Oslo, Norway.
Stephen E GilmanSocial and Behavioral Sciences Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Rockville, MD, USA.
Golam M KhandakerDepartment of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Deshayne B FellSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada.
Ian ColmanSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada.
Norwegian Institute of Public Health · NOJohns Hopkins University · USOsloMet – Oslo Metropolitan University · NOUniversity of Cambridge · GBUniversity of Oslo · NOUniversity of Ottawa · CA

Funding

Social determinants of child development and mental healthZIAHD008976 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI GILMAN, STEPHEN · 2018 to 2025
$14.3M
Intramural NIH HHS ZIA HD008976Medical Research Council MC_PC_17213Medical Research Council MR/S037675/1Wellcome TrustWellcome Trust 201486/Z/16/Z
6 · The paper itself

Abstract

backgroundFew studies have examined how parenting influences the associations between prenatal maternal stress and children's mental health. The objectives of this study were to examine the sex-specific associations between prenatal maternal stress and child internalizing and externalizing symptoms, and to assess the moderating effects of parenting behaviors on these associations.

methodsThis study is based on 15 963 mother-child dyads from the Norwegian Mother, Father, and Child Cohort Study (MoBa). A broad measure of prenatal maternal stress was constructed using 41 self-reported items measured during pregnancy. Three parenting behaviors (positive parenting, inconsistent discipline, and positive involvement) were assessed by maternal report at child age 5 years. Child symptoms of internalizing and externalizing disorders (depression, anxiety, attention-deficit hyperactivity disorder, conduct disorder, and oppositional-defiant disorder) were assessed by maternal report at age 8. Analyses were conducted using structural equation modeling techniques.

resultsPrenatal maternal stress was associated with child internalizing and externalizing symptoms at age 8; associations with externalizing symptoms differed by sex. Associations between prenatal maternal stress and child depression, and conduct disorder and oppositional-defiant disorder in males, became stronger as levels of inconsistent discipline increased. Associations between prenatal maternal stress and symptoms of attention-deficit hyperactivity disorder in females were attenuated as levels of parental involvement increased.

conclusionsThis study confirms associations between prenatal maternal stress and children's mental health outcomes, and demonstrates that these associations may be modified by parenting behaviors. Parenting may represent an important intervention target for improving mental health outcomes in children exposed to prenatal stress.

Indexed as

MothersParentingChildChild, PreschoolCohort StudiesFathersFemaleHumansMaleParentsPregnancyExternalizingfetal programinginternalizingMoBaparentingprenatal stress

Identifiers

PMID37310302
PMCPMC10264827
OpenAlexW3214856856

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.