Evidence map›Paper›PMID 37310284›Full record

ArticleAntimicrobial agents and chemotherapy2023

Genomic Epidemiology of Carbapenem-Resistant

Clement Kin-Ming Tsui, Fatma Ben Abid, Khalil Al Ismail, Christi Lee McElheny, Muna Al Maslamani, Ali S Omrani, Yohei Doi

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Emergence of ST383 carbapenem-resistantJAC-antimicrobial resistance · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Prevalence and features of hypervirulentInfection and immunity · 2025
    Review
  13. Characterization ofJAC-antimicrobial resistance · 2024
    Article
  14. Journal of medical microbiology · 2024
    Article
  15. Article
  16. Article
  17. Clinical and molecular characteristics of Klebsiella pneumoniae infection in a tertiary general hospital of Wuhan, China.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  18. Dissemination ofInfection and drug resistance · 2024
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Clement Kin-Ming Tsui *Infectious Diseases Research Laboratory, National Centre for Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.ORCID 0000-0001-5129-1037
Fatma Ben Abid *Weill Cornell Medicine-Qatar, Doha, Qatar.
Khalil Al IsmailCommunicable Diseases Center, Hamad Medical Corporation, Doha, Qatar.
Christi Lee McElhenyDivision of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Muna Al MaslamaniCommunicable Diseases Center, Hamad Medical Corporation, Doha, Qatar.
Ali S OmraniCommunicable Diseases Center, Hamad Medical Corporation, Doha, Qatar.ORCID 0000-0001-5309-6358
Yohei DoiDivision of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-9620-2525

Funding

Colistin-resistant Acinetobacter baumanniiR01AI104895 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DOI, YOHEI, ERNST, ROBERT K · 2014 to 2024
$4.2M
Study Network of Acinetobacter as a Carbapenem-Resistant Pathogen (SNAP)R21AI135522 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DOI, YOHEI · 2018 to 2019
$460k
Mechanisms of cefiderocol resistanceR21AI151362 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DOI, YOHEI · 2020 to 2021
$420k
Medical Research Council MRC-16134/16NIAID NIH HHS R01 AI104895NIAID NIH HHS R21 AI135522NIAID NIH HHS R21 AI151362
6 · The paper itself

Abstract

The emergence of carbapenem-resistant, hypervirulent Klebsiella pneumoniae is a new threat to health care. We studied the molecular epidemiology of carbapenem-resistant Klebsiella pneumoniae isolates in Qatar using whole-genome sequence data. We also characterized the prevalence and genetic basis of hypervirulent phenotypes and established the virulence potential using a Galleria mellonella model. Of 100 Klebsiella isolates studied, NDM and OXA-48 were the most common carbapenemases. Core genome single-nucleotide polymorphism (SNP) analysis indicated the presence of diverse sequence types and clonal lineages; isolates belonging to Klebsiella quasipneumoniae subsp.

Indexed as

Klebsiella InfectionsKlebsiella pneumoniaeAnti-Bacterial Agentsbeta-LactamasesCarbapenemsGenomicsHumansKlebsiellaPlasmidsQatarAnti-Bacterial Agentsbeta-LactamasesCarbapenemscarbapenem resistancegenomicshybrid plasmidKlebsiellamolecular epidemiologyvirulence

Identifiers

PMID37310284
PMCPMC10353355

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.