Evidence map›Paper›PMID 37310263›Full record

ArticleJournal of virology2023

Analysis of the Contribution of 6-mer Seed Toxicity to HIV-1-Induced Cytopathicity.

Aparajitha Vaidyanathan, Harry E Taylor, Thomas J Hope, Richard T D'Aquila, Elizabeth T Bartom, Judd F Hultquist, Marcus E Peter

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. CD95/Fas ligand induced toxicity.Biochemical Society transactions · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Aparajitha VaidyanathanDepartment of Medicine, Division Hematology/Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Harry E TaylorDivision of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Thomas J HopeDepartment of Cell & Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0001-7183-8319
Richard T D'AquilaDivision of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Elizabeth T BartomDepartment of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Judd F HultquistDivision of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Marcus E PeterDepartment of Medicine, Division Hematology/Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0003-3216-036X
Northwestern University · US

Funding

Virology and Immunology Technology CoreP30AI117943 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Sahera Dirajlal-Fargo · 2015 to 2026
$38.4M
Project 3U54AI170792 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Nevan J Krogan · 2022 to 2026
$35.7M
Functionally Defining HIV-Host Interactions During the Early HIV-1 LifecycleR01AI150998 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BIENIASZ, PAUL D., HOPE, THOMAS · 2020 to 2024
$6.8M
Deciphering the Role of CPSF6 in HIV InfectionR01AI165236 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HULTQUIST, JUDD F · 2021 to 2025
$2.0M
6mer seed toxicity and AIDSR21AI150910 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PETER, MARCUS E. · 2020 to 2021
$436k
NIAID NIH HHS P30 AI117943NIAID NIH HHS R01 AI150998NIAID NIH HHS R01 AI165236NIAID NIH HHS R21 AI150910NIAID NIH HHS U54 AI170792
6 · The paper itself

Abstract

HIV-1 (HIV) infects CD4

Indexed as

HIV-1HIV InfectionsMicroRNAsHumansRNA-Induced Silencing ComplexVirus LatencyMicroRNAsRNA-Induced Silencing ComplexAIDScell deathRISCRNAiRNA toxicity

Identifiers

PMID37310263
PMCPMC10373551
OpenAlexW4380422467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.