Evidence map›Paper›PMID 37310227›Full record

ArticleJournal of bacteriology2023

OprF Impacts Pseudomonas aeruginosa Biofilm Matrix eDNA Levels in a Nutrient-Dependent Manner.

Erin K Cassin, Sophia A Araujo-Hernandez, Dena S Baughn, Melissa C Londono, Daniela Q Rodriguez, Natalie S Al-Otaibi, Aude Picard, Julien R C Bergeron, Boo Shan Tseng

Open access · hybridAbstract read
In one paragraph

Article in Journal of bacteriology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Targeting Outer Membrane Vesicles ofJournal of microbiology and biotechnology · 2026
    Review
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  5. EPY001, a Novel Monoclonal Antibody AgainstInternational journal of molecular sciences · 2025
    Article
  6. Article
  7. Frontiers in cellular and infection microbiology · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Erin K CassinSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, USA.
Sophia A Araujo-HernandezSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, USA.
Dena S BaughnSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, USA.
Melissa C LondonoSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, USA.
Daniela Q RodriguezSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, USA.
Natalie S Al-OtaibiDepartment of Biological Sciences, Birkbeck, University of London, London, United Kingdom.
Aude PicardSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, USA.
Julien R C BergeronRandall Centre for Cell and Molecular Biophysics, King's College London, London, United Kingdom.
Boo Shan TsengSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, USA.ORCID 0000-0001-7563-0232
University of Nevada, Las Vegas · USBirkbeck, University of London · GBKing's College London · GB

Funding

Outreach/Diversity/Pipeline ProjectP20GM103440 · NIGMS · UNIVERSITY OF NEVADA RENO · PI Jonathan E. Baker · 2012 to 2026
$58.0M
Matrix-associated proteins in biofilm tolerance: Psl and ecotinK22AI121097 · NIAID · UNIVERSITY OF NEVADA LAS VEGAS · PI TSENG, BOO SHAN · 2016 to 2017
$268k
6 · The paper itself

Abstract

The biofilm matrix is composed of exopolysaccharides, eDNA, membrane vesicles, and proteins. While proteomic analyses have identified numerous matrix proteins, their functions in the biofilm remain understudied compared to the other biofilm components. In the Pseudomonas aeruginosa biofilm, several studies have identified OprF as an abundant matrix protein and, more specifically, as a component of biofilm membrane vesicles. OprF is a major outer membrane porin of P. aeruginosa cells. However, current data describing the effects of OprF in the P. aeruginosa biofilm are limited. Here, we identify a nutrient-dependent effect of OprF in static biofilms, whereby Δ

Indexed as

Extracellular Polymeric Substance MatrixPseudomonas aeruginosaBacterial ProteinsBiofilmsDNAGlucoseNutrientsProteomicsSodium ChlorideBacterial ProteinsDNAGlucoseNutrientsSodium Chloridebiofilm maintenancebiofilm matrix proteinseDNAnutrient-dependentOprF

Identifiers

PMID37310227
PMCPMC10367591
OpenAlexW4380421835

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.