Evidence map›Paper›PMID 37309982›Full record

ReviewThe Journal of international medical research2023

Viewpoint about biologic agents for psoriasis: are they immunosuppressants or immunomodulators?

Dea Metko, Tiago Torres, Ronald Vender

Abstract readReview
In one paragraph

Review in The Journal of international medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. IL-23 blockade in a patient with psoriasis andSAGE open medical case reports · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dea MetkoMichael G. DeGroote School of Medicine, McMaster University, Hamilton, Canada.ORCID 0000-0001-6617-6621
Tiago TorresInstituto de Ciências Biomédicas Abel Salazar, University of Porto, Porto, Portugal.ORCID 0000-0003-0404-0870
Ronald VenderDermatrials Research Inc., and Venderm Consulting, Hamilton, Canada.ORCID 0000-0002-2624-2724

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past two decades, promising advancements have emerged in the field of psoriasis management. Most notably, highly effective targeted biologic therapies that offered significant breakthroughs in the management of psoriasis have been developed. One of the most challenging components of marketing and prescribing these biologic therapies has been in classifying them as immunomodulators or immunosuppressants. The purpose of this narrative review was to discuss the features that distinguish immunomodulators from immunosuppressants to successfully categorize the biologic therapies used for psoriasis management and subsequently enhance patient and physician understanding of the risks associated with the use of these drugs.

Indexed as

Immunosuppressive AgentsPsoriasisAdjuvants, ImmunologicBiological FactorsHumansImmunologic FactorsAdjuvants, ImmunologicBiological FactorsImmunologic FactorsImmunosuppressive Agentsbiologic therapyimmunomodulatorimmunosuppressantinterleukin 12interleukin 17interleukin 23Psoriasistumor necrosis factor alpha

Identifiers

PMID37309982
PMCPMC10286538

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.