Evidence map›Paper›PMID 37309878›Full record

ArticleLa Medicina del lavoro2023

Excess Total Mortality in Italy: An Update to February 2023 with Focus on Working Ages.

Gianfranco Alicandro, Alberto Giovanni Gerli, Stefano Centanni, Giuseppe Remuzzi, Carlo La Vecchia

Abstract read
In one paragraph

Article in La Medicina del lavoro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gianfranco AlicandroDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy. gianfranco.alicandro@istat.it.
Alberto Giovanni GerliDepartment of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy. alberto.gerli@unimi.it.
Stefano CentanniRespiratory Unit, Department of Health Sciences, ASST Santi Paolo e Carlo, Università degli Studi di Milano, Milan, Italy. stefano.centanni@unimi.it.
Giuseppe RemuzziIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy. giuseppe.remuzzi@marionegri.it.
Carlo La VecchiaDepartment of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy . carlo.lavecchia@unimi.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundItaly had a persistent excess of total mortality up to July 2022. This study provides updated estimates of excess mortality in Italy until February 2023.

methodsMortality and population data from 2011 to 2019 were used to estimate the number of expected deaths during the pandemic. Expected deaths were obtained using over-dispersed Poisson regression models, fitted separately for men and women, including calendar year, age group, and a smoothed function of the day of the year as predictors. The excess deaths were then obtained by calculating the difference between observed and expected deaths and were computed at all ages and working ages (25-64 years).

resultsWe estimated 26,647 excess deaths for all ages and 1248 for working ages from August to December 2022, resulting in a percent excess mortality of 10.2% and 4.7%, respectively. No excess mortality was detected in January and February 2023.

conclusionsOur study indicates substantial excess mortality beyond those directly attributed to COVID-19 during the BA.4 and BA.5 Omicron wave in the latter half of 2022. This excess could be attributed to additional factors, such as the heatwave during the summer of 2022 and the early onset of the influenza season.

Indexed as

COVID-19FemaleHumansItalyMalePandemicsSeizures

Identifiers

PMID37309878
PMCPMC10281071

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.