Evidence map›Paper›PMID 37309838›Full record

ArticleJournal of magnetic resonance imaging : JMRI2024

Evaluating a Phase-Specific Approach to Aortic Flow: A 4D Flow MRI Study.

Mitch J F G Ramaekers, Jos J M Westenberg, Max F G H M Venner, Joe F Juffermans, Hans C van Assen, Bastiaan J C Te Kiefte, Bouke P Adriaans, Hildo J Lamb, Joachim E Wildberger, Simon Schalla

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In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Mitch J F G RamaekersDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0003-4830-4508
Jos J M WestenbergDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0003-1946-1715
Max F G H M VennerDepartment of Cardiology, Maastricht University Medical Center+, Maastricht, The Netherlands.
Joe F JuffermansDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0001-8914-8279
Hans C van AssenDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0003-4907-904X
Bastiaan J C Te KiefteDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Bouke P AdriaansDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands.ORCID 0000-0002-4409-6206
Hildo J LambDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-6969-2418
Joachim E WildbergerDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands.
Simon SchallaDepartment of Cardiology, Maastricht University Medical Center+, Maastricht, The Netherlands.
Leiden University Medical Center · NLMaastricht University · NLMaastricht University Medical Centre · NL

Funding

Hartstichting CVON-2017-07-RADAR
6 · The paper itself

Abstract

backgroundAortic flow parameters can be quantified using 4D flow MRI. However, data are sparse on how different methods of analysis influence these parameters and how these parameters evolve during systole. PURPOSE: To assess multiphase segmentations and multiphase quantification of flow-related parameters in aortic 4D flow MRI. STUDY TYPE: Prospective. POPULATION: 40 healthy volunteers (50% male, 28.9 ± 5.0 years) and 10 patients with thoracic aortic aneurysm (80% male, 54 ± 8 years). FIELD STRENGTH/SEQUENCE: 4D flow MRI with a velocity encoded turbo field echo sequence at 3 T. ASSESSMENT: Phase-specific segmentations were obtained for the aortic root and the ascending aorta. The whole aorta was segmented in peak systole. In all aortic segments, time to peak (TTP; for flow velocity, vorticity, helicity, kinetic energy, and viscous energy loss) and peak and time-averaged values (for velocity and vorticity) were calculated. STATISTICAL TESTS: Static vs. phase-specific models were assessed using Bland-Altman plots. Other analyses were performed using phase-specific segmentations for aortic root and ascending aorta. TTP for all parameters was compared to TTP of flow rate using paired t-tests. Time-averaged and peak values were assessed using Pearson correlation coefficient. P < 0.05 was considered statistically significant.

resultsIn the combined group, velocity in static vs. phase-specific segmentations differed by 0.8 cm/sec for the aortic root, and 0.1 cm/sec (P = 0.214) for the ascending aorta. Vorticity differed by 167 sec DATA

conclusionStatic 4D flow MRI segmentation yields comparable results as multiphase segmentation for flow-related parameters, eliminating the need for time-consuming multiple segmentations. However, multiphase quantification is necessary for assessing peak values of aortic flow-related parameters. LEVEL OF EVIDENCE: 2 TECHNICAL EFFICACY STAGE: 3.

Indexed as

AortaHemodynamicsAorta, ThoracicBlood Flow VelocityFemaleHumansMagnetic Resonance ImagingMaleProspective Studies4D flow MRIaortablood flowMRI

Identifiers

PMID37309838
OpenAlexW4380421787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.