Evidence map›Paper›PMID 37309831›Full record

ArticleClinical pediatrics2024

Multisystem Inflammatory Syndrome in Children: Two Years' Worth of Learning.

Seth McKenzie Alexander, John Bryan Lykes, Christopher Nassef, Jennifer K E Whitham, Jason G Ho, Bridget B Donell

Abstract read
In one paragraph

Article in Clinical pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Post-MIS-C cardiovascular outcomes: a systematic review.European journal of pediatrics · 2026
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Seth McKenzie AlexanderDepartment of Pediatrics, Division of Pediatric Critical Care and Hospital Medicine, WakeMed Children's Hospital, Raleigh, NC, USA.ORCID 0000-0002-2706-2696
John Bryan LykesDepartment of Pediatrics, Division of Pediatric Critical Care and Hospital Medicine, WakeMed Children's Hospital, Raleigh, NC, USA.
Christopher NassefDepartment of Pediatrics, Division of Pediatric Critical Care and Hospital Medicine, WakeMed Children's Hospital, Raleigh, NC, USA.
Jennifer K E WhithamDepartment of Pediatrics, Division of Pediatric Cardiology, WakeMed Children's Hospital, Raleigh, NC, USA.
Jason G HoDepartment of Pediatrics, Division of Pediatric Cardiology, WakeMed Children's Hospital, Raleigh, NC, USA.
Bridget B DonellDepartment of Pediatrics, Division of Pediatric Critical Care and Hospital Medicine, WakeMed Children's Hospital, Raleigh, NC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multisystem inflammatory syndrome in children (MIS-C) is a life-threatening sequela of SARS-CoV-2 infection. Limited data are available regarding risk-stratification or long-term outcomes in MIS-C. This study sought to determine associations between serologic markers and severity of illness and understand long-term cardiac outcomes. This series includes 46 cases (mean age 8.1 years; 63.0% male) of MIS-C. Pearson's chi-squared analysis showed an erythrocyte sedimentation rate (ESR) greater than 30 mm/h and 50 mm/h were disproportionately associated with pediatric intensive care unit (PICU) admission (χ

Indexed as

COVID-19SARS-CoV-2ChildFemaleHospitalizationHumansMaleSystemic Inflammatory Response SyndromeCOVID-19critical carehospital medicineMIS-Cpediatrics

Identifiers

PMID37309831
PMCPMC10696906

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.