Evidence map›Paper›PMID 37309499›Full record

ArticleSpine surgery and related research2023

Preoperative Base Excess as a Predictor of Perioperative Complications in Patients with Nonidiopathic Scoliosis who Have High Risk Associated with General Anesthesia.

Yutaro Kanda, Kenichiro Kakutani, Moritoki Egi, Zhongying Zhang, Takashi Yurube, Yoshiki Takeoka, Kunihiko Miyazaki, Hiroki Ohnishi, Tomoya Matsuo, Masao Ryu and 2 more

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Article in Spine surgery and related research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yutaro KandaDepartment of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Kenichiro KakutaniDepartment of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Moritoki EgiDepartment of Anesthesiology, Kobe University Hospital, Kobe, Japan.
Zhongying ZhangDepartment of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Takashi YurubeDepartment of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Yoshiki TakeokaDepartment of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Kunihiko MiyazakiDepartment of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Hiroki OhnishiDepartment of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Tomoya MatsuoDepartment of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Masao RyuDepartment of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Yuichi HoshinoDepartment of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Ryosuke KurodaDepartment of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Kobe University · JPKobe University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Patients with nonidiopathic scoliosis often have a high risk associated with general anesthesia because of cardiac or pulmonary dysfunction secondary to underlying diseases. Base excess has been reported as a predictor in the management of trauma and cancer, although not yet in scoliosis. This study was performed to clarify the surgical outcomes and the association of perioperative complications with base excess in patients with nonidiopathic scoliosis who have a high risk associated with general anesthesia. Methods: Patients with nonidiopathic scoliosis who were referred to our institution from 2009 to 2020 because of their high risk associated with general anesthesia were retrospectively enrolled. High-risk factors for anesthesia were determined by a senior anesthesiologist and categorized into circulatory or pulmonary dysfunction. Perioperative complications were analyzed using the Clavien-Dindo classification; severe complications were defined as grade ≥III. We investigated high-risk factors for anesthesia, underlying diseases, preoperative and postoperative Cobb angle, surgery-related factors, base excess, and postoperative management. These variables were statistically compared between patients with and without complications. Results: Thirty-six patients (mean age, 17.9 years old; range, 11-40 years old) were enrolled (two patients declined surgery). High-risk factors were circulatory dysfunction in 16 patients and pulmonary dysfunction in 20 patients. The mean Cobb angle improved from 85.1° (36°-128°) preoperatively to 43.6° (9°-83°) postoperatively. Three intraoperative complications and 23 postoperative complications occurred in 20 (55.6%) patients. Severe complications occurred in 10 (27.8%) patients. All patients underwent postoperative intensive care unit management after posterior all-screw construction. A large preoperative Cobb angle ( Conclusions: Patients with nonidiopathic scoliosis who have a high risk associated with general anesthesia have a higher complication rate. Preoperative large deformity and base excess (>3 or <-3 mEq/L) could be predictors of complications.

Indexed as

base excesscirculatory dysfunctionhigh risk associated with general anesthesianeuromuscular scoliosisnonidiopathic scoliosispostoperative complicationpulmonary dysfunctionsyndromic scoliosis

Identifiers

PMID37309499
PMCPMC10257964
OpenAlexW4313025891

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.