Evidence map›Paper›PMID 37309291›Full record

SynthesisInternational wound journal2023

Intrawound vancomycin powder in orthopaedic surgery as surgical site wound infection prophylaxis: A meta-analysis.

Bin Wang, Songlin Li, Jinkang Zhang, Di Wu, Xiaogang Huang, Dongzhou Liu, Junjie Du

RetractedAbstract readMeta-AnalysisRetracted Publication
In one paragraph

Synthesis in International wound journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Bin WangOrthopedics Department, Air Force Medical Center, Beijing, China.
Songlin LiOrthopedics Department, Air Force Medical Center, Beijing, China.
Jinkang ZhangOrthopedics Department, Air Force Medical Center, Beijing, China.
Di WuOrthopedics Department, Air Force Medical Center, Beijing, China.
Xiaogang HuangOrthopedics Department, Air Force Medical Center, Beijing, China.
Dongzhou LiuOrthopedics Department, Air Force Medical Center, Beijing, China.
Junjie DuOrthopedics Department, Air Force Medical Center, Beijing, China.ORCID https://orcid.org/0009-0005-4141-2380

Funding

PLA Military Logistics Research Foundation BKJ20J004
6 · The paper itself

Abstract

A meta-analysis research was executed to appraise the consequence of intrawound vancomycin powder (IWVP) in orthopaedic surgery (OPS) as surgical site wound infection (SSWI) prophylaxis. Inclusive literature research till March 2023 was carried out and 2756 interconnected researches were revised. Of the 18 picked researches enclosed 13 214 persons with OPS were in the used researches' starting point, 5798 of them were utilising IWVP, and 7416 were control. Odds ratio (OR) in addition to 95% confidence intervals (CIs) were used to appraise the consequence of the IWVP in OPS as SSWI prophylaxis by the dichotomous approaches and a fixed or random model. IWVP had significantly lower SSWIs (OR, 0.61; 95% CI, 0.50-0.74, P < .001), deep SSWIs (OR, 0.57; 95% CI, 0.36-0.91, P = .02), and superficial SSWIs (OR, 0.67; 95% CI, 0.46-0.98, P = .04) compared with control in persons with OPS. IWVP had significantly lower SSWIs, deep SSWIs, and superficial SSWIs compared with control in persons with OPS. However, when interacting with its values, caution must be taken and more research is needed to confirm this finding.

Indexed as

Orthopedic ProceduresVancomycinAnti-Bacterial AgentsAntibiotic ProphylaxisHumansPowdersSurgical Wound InfectionAnti-Bacterial AgentsPowdersVancomycinintrawound vancomycin powderorthopaedic surgeryprophylaxissurgical site infection

Identifiers

PMID37309291
PMCPMC10588340

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.