Evidence map›Paper›PMID 37308932›Full record

ArticleCardiovascular diabetology2023

Normal-weight visceral obesity promotes a higher 10-year atherosclerotic cardiovascular disease risk in patients with type 2 diabetes mellitus-a multicenter study in China.

Jia Zheng, Ye Hu, Hanwen Xu, Yu Lei, Jieji Zhang, Qidong Zheng, Li Li, Weiping Tu, Riqiu Chen, Qiongyao Guo and 5 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Cardiovascular diabetology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
15.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 1 country.

Jia ZhengGeriatric Medicine Center, Key Laboratory of Endocrine Gland Diseases of Zhejiang Province, Department of Endocrinology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, 310014, Zhejiang, People's Republic of China.
Ye HuGeriatric Medicine Center, Key Laboratory of Endocrine Gland Diseases of Zhejiang Province, Department of Endocrinology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, 310014, Zhejiang, People's Republic of China.
Hanwen XuGeriatric Medicine Center, Key Laboratory of Endocrine Gland Diseases of Zhejiang Province, Department of Endocrinology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, 310014, Zhejiang, People's Republic of China.
Yu LeiGeriatric Medicine Center, Key Laboratory of Endocrine Gland Diseases of Zhejiang Province, Department of Endocrinology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, 310014, Zhejiang, People's Republic of China.
Jieji ZhangDepartment of Endocrinology, Fenghua District Traditional Chinese Medicine Hospital of Ningbo, Ningbo, 315500, China.
Qidong ZhengDepartment of Endocrinology, Yuhuan Second People's Hospital, Taizhou, 317605, China.
Li LiDepartment of Endocrinology and Metabolism, Ningbo First Hospital, Ningbo, 315000, China.
Weiping TuDepartment of Endocrinology, Shaoxing Shangyu People's Hospital, Shaoxing, 312300, China.
Riqiu ChenDepartment of Endocrinology, Lishui People's Hospital, Lishui, 323000, China.
Qiongyao GuoDepartment of Endocrinology, The People's Hospital of Putuo Zhoushan, Zhoushan, 316100, China.
Xunxiong ZangDepartment of Endocrinology, Yueqing People's Hospital, Wenzhou, 325600, China.
Qiaoying YouDepartment of Endocrine and Metabolism, Shaoxing People's Hospital, Shaoxing, 312000, China.
Zhiyong XuDepartment of Endocrinology, Xianju people's hospital, Taizhou, 317300, China.
Qiang ZhouDepartment of Endocrinology, The First Hospital of Jiaxing, Jiaxing, 314000, China.
Xiaohong WuGeriatric Medicine Center, Key Laboratory of Endocrine Gland Diseases of Zhejiang Province, Department of Endocrinology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, 310014, Zhejiang, People's Republic of China. drxhwu@163.com.ORCID 0000-0001-5984-3342
Zhejiang Provincial People's Hospital · CNShaoxing People's Hospital · CNFirst Hospital of Jiaxing · CNLishui City People's Hospital · CNNantong University · CNNingbo First Hospital · CNTaizhou Second People's Hospital · CNYueqing People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVisceral obesity is associated with high cardiovascular events risk in type 2 diabetes mellitus (T2DM). Whether normal-weight visceral obesity will pose a higher atherosclerotic cardiovascular disease (ASCVD) risk than body mass index (BMI)-defined overweight or obese counterparts with or without visceral obesity remains unclear. We aimed to explore the relationship between general obesity and visceral obesity and 10-year ASCVD risk in patients with T2DM.

methodsPatients with T2DM (6997) who satisfied the requirements for inclusion were enrolled. Patients were considered to have normal weight when 18.5 kg/m

resultsIn patients with T2DM, subjects with normal-weight visceral obesity had the highest 10-year ASCVD risk among the six groups, which had more than a 2-fold or 3-fold higher OR than those who were overweight or obese according to BMI but did not have visceral obesity (all P < 0.05). The VFA threshold for high 10-year ASCVD risk was 90 cm

conclusionsT2DM patients with normal-weight visceral obesity had a higher 10-year ASCVD risk than BMI-defined overweight or obese counterparts with or without visceral obesity, which should initiate standardised management for ASCVD primary prevention.

Indexed as

AtherosclerosisCardiovascular DiseasesDiabetes Mellitus, Type 2ChinaCholesterol, HDLHumansObesityObesity, AbdominalOverweightCholesterol, HDLAtherosclerotic cardiovascular disease riskMulticentre studyNormal weightObesity paradoxType 2 diabetes mellitusVisceral obesity

Identifiers

PMID37308932
PMCPMC10262529
OpenAlexW4380364392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.