ArticleBMC oral health2023
Orofacial function and temporomandibular disorders in Parkinson's Disease: a case-controlled study.
Article in BMC oral health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05356845 (Oral Health, Orofacial Function and Oral Health Care in Patients With Parkinson's Disease), which is not on this map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Oral Health, Orofacial Function and Oral Health Care in Patients With Parkinson's Disease
Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Temporomandibular Disorder-like Pain in Parkinson's Disease Is Associated with Motor Symptom Severity and Disability Levels.Journal of clinical medicine · 2026Article
- Characteristics of Swallowing Function in People with Parkinson's Disease: A Scoping Review.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Oral health and oral microbiota composition in patients with Parkinson's disease: a case‒control study.Journal of oral microbiology · 2026Article
- Comparison of facial muscle activity between younger and older Japanese adults: A cross-sectional study.PloS one · 2026Article
- Maximum Muscle Output and Electromyographic Activity of Masticatory Muscles in Persons With Parkinson's Disease. A Case-Control Study.Journal of oral rehabilitation · 2025Article
- Self-Perception of Drooling Impact in People with Parkinson's Disease: A Case-Control and Cross-Sectional Study.Movement disorders clinical practice · 2025Article
- Oral health implications in Parkinson's disease.NPJ Parkinson's disease · 2025Review
- Temporomandibular Joint Dislocation in Patients With Parkinsonism: A Report of Two Cases.Cureus · 2025Article
- Motor deficits and brain pathology in the Parkinson's disease mouse model hA53Ttg.Frontiers in neuroscience · 2024Article
- Brainstem Modulates Parkinsonism-Induced Orofacial Sensorimotor Dysfunctions.International journal of molecular sciences · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe difficulties and challenges faced by people with Parkinson's disease (PD) in performing daily orofacial function are not systematically investigated. In this study, specific orofacial non-motor and motor symptoms and functions were systematically examined in PD patients in comparison to a matched control group.
methodsThe clinical case-controlled study was conducted from May 2021 to October 2022 and included persons with PD and age- and gender-matched persons without PD. The participants with PD were outpatients diagnosed with PD at the Department of Neurology at Bispebjerg University Hospital in Copenhagen, Denmark. The participants underwent a systematic clinical and relevant self-assessment of the orofacial function and temporomandibular disorders (TMD). The primary outcomes were objective and subjective assessments of the general orofacial function, mastication, swallowing, xerostomia and drooling. The secondary outcomes were the prevalence of TMD and orofacial pain. The difference in outcome measures between the two groups was analysed using chi-square and Mann-Whitney U test.
resultsThe study included 20 persons with PD and 20 age- and gender-matched persons without PD. Both objectively and subjectively, persons with PD had poorer orofacial function than the control group. Persons with PD had also a significantly more severe limitation of jaw mobility and jaw function. The objective masticatory function was also significantly reduced for persons with PD compared to the control group, and 60% of persons with PD found it difficult to eat foods with certain consistencies while 0% of the control group reported that problem. Persons with PD could swallow less water per second and the average swallowing event was significantly longer for PD persons. Even though PD persons reported more xerostomia (58% for persons with PD and 20% for control persons), they also reported significantly more drooling than the control group. Additionally, orofacial pain was more prevalent in PD persons.
conclusionsPersons with PD have a compromised orofacial function. Furthermore, the study indicates a link between PD and orofacial pain. In order to screen and treat persons with PD accordingly, healthcare professionals should be aware of and address these limitations and symptoms.
trial registrationThe trial was approved by the Regional Committee on Research Health Ethics of the Capital Region (H-20,047,464), the Danish Data Protection Agency (514 - 0510/20-3000), and registered at ClinicalTrials.gov (NCT05356845).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.