Evidence map›Paper›PMID 37308844›Full record

ArticleBMC nephrology2023

Predicting hyperkalemia in patients with advanced chronic kidney disease using the XGBoost model.

Hsin-Hsiung Chang, Jung-Hsien Chiang, Chun-Chieh Tsai, Ping-Fang Chiu

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Hsin-Hsiung ChangDivision of Nephrology, Department of Internal Medicine, Antai Medical Care Corporation Antai Tian-Sheng Memorial Hospital, Pingtung County, Taiwan.
Jung-Hsien ChiangDepartment of Computer Science and Information Engineering, National Cheng Kung University, Tainan, Taiwan. jchiang@mail.ncku.edu.tw.
Chun-Chieh TsaiDivision of Nephrology, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan.
Ping-Fang ChiuDivision of Nephrology, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan. 68505@cch.org.tw.
National Cheng Kung University · TWChanghua Christian Hospital · TWMingDao University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHyperkalemia is a common complication of chronic kidney disease (CKD). Hyperkalemia is associated with mortality, CKD progression, hospitalization, and high healthcare costs in patients with CKD. We developed a machine learning model to predict hyperkalemia in patients with advanced CKD at an outpatient clinic.

methodsThis retrospective study included 1,965 advanced CKD patients between January 1, 2010, and December 31, 2020 in Taiwan. We randomly divided all patients into the training (75%) and testing (25%) datasets. The primary outcome was to predict hyperkalemia (K

resultsIn a human-machine competition of hyperkalemia prediction, the AUC, PPV, and accuracy of the XGBoost model were 0.867 (95% confidence interval: 0.840-0.894), 0.700, and 0.933, which was significantly better than that of our clinicians. There were four variables that were chosen as high-ranking variables in XGBoost and logistic regression models, including hemoglobin, the serum potassium level in the previous visit, angiotensin receptor blocker use, and calcium polystyrene sulfonate use.

conclusionsThe XGBoost model provided better predictive performance for hyperkalemia than physicians at the outpatient clinic.

Indexed as

HyperkalemiaRenal Insufficiency, ChronicAmbulatory Care FacilitiesHumansKidneyRetrospective StudiesChronic kidney diseaseHyperkalemiaMachine learning

Identifiers

PMID37308844
PMCPMC10259360
OpenAlexW4380356754

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.