Evidence map›Paper›PMID 37308760›Full record

ReviewSurgical endoscopy2023

Long-term outcomes following Dor, Toupet, and Nissen fundoplication: a network meta-analysis of randomized controlled trials.

Yung Lee, Umair Tahir, Lea Tessier, Kevin Yang, Taaha Hassan, Jerry Dang, Matthew Kroh, Dennis Hong

Abstract readReviewNetwork Meta-Analysis
PubMed Publisher
In one paragraph

Review in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Yung LeeDivision of General Surgery, McMaster University, Hamilton, ON, Canada.
Umair TahirDivision of General Surgery, McMaster University, Hamilton, ON, Canada.
Lea TessierDivision of General Surgery, McMaster University, Hamilton, ON, Canada.
Kevin YangDivision of General Surgery, McMaster University, Hamilton, ON, Canada.
Taaha HassanDivision of General Surgery, McMaster University, Hamilton, ON, Canada.
Jerry DangDigestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA.
Matthew KrohDigestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA.
Dennis HongDivision of General Surgery, McMaster University, Hamilton, ON, Canada. dennishong70@gmail.com.ORCID 0000-0003-1792-1255
McMaster University · CACleveland Clinic · USHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the surgical management of GERD, the traditional procedure is laparoscopic total (Nissen) fundoplication. However, partial fundoplication has been advocated as providing similar reflux control while potentially minimizing dysphagia. The comparative outcomes of different approaches to fundoplication are a topic of ongoing debate and long-term outcomes remain uncertain. This study aims to compare long-term gastroesophageal reflux disease (GERD) related outcomes following different fundoplication procedures.

methodsMEDLINE, EMBASE, PubMed, and CENTRAL databases were searched up to November 2022 to identify randomized controlled trials (RCTs) comparing different types of fundoplications reporting long-term (> 5 years) outcomes. The primary outcome was incidence of dysphagia. Secondary outcomes included incidence of heartburn/reflux, regurgitation, inability to belch, abdominal bloating, reoperation, and patient satisfaction. DataParty, which uses Python 3.8.10 was used to perform the network meta-analysis. We evaluated the overall certainty of evidence with the GRADE framework.

results13 RCTs were included, with 2063 patients across Nissen (360°), Dor (anterior 180°-200°), and Toupet (posterior 270°) fundoplications. Network estimates demonstrated that Toupet had lower incidence of dysphagia compared to Nissen (OR 0.285; 95% CrI 0.06-0.958). There were no differences in dysphagia between Toupet and Dor (OR 0.473, 95% CrI 0.072-2.835) or between Dor and Nissen (OR 1.689, 95% CrI 0.403-7.699). The three fundoplication types were comparable in all other outcomes.

conclusionsAll three approaches of fundoplication share similar long-term outcomes, with the Toupet fundoplication likely providing the best long-term durability with lowest odds of developing postoperative dysphagia.

Indexed as

Deglutition DisordersGastroesophageal RefluxLaparoscopyFundoplicationHumansNeoplasm Recurrence, LocalPostoperative ComplicationsRandomized Controlled Trials as TopicTreatment OutcomeDorFundoplicationLong termNetwork meta-analysisNissenToupet

Identifiers

PMID37308760
OpenAlexW4380362958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.