Observational studyNeurocritical care2023
The Loss of Temporal Muscle Volume is Associated with Poor Outcome in Patients with Subarachnoid Hemorrhage: An Observational Cohort Study.
Observational study in Neurocritical care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.
- Association between temporalis muscle thickness and functional outcomes in acute stroke: A meta-analysis and GRADE approach.The journal of nutrition, health & aging · 2025Pooled it
- Value of temporal muscle thickness in predicting outcomes of stroke: a systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- Temporalis Muscle Thickness as a Prognostic Marker in Acute Ischemic Stroke: A Systematic Review.Journal of clinical medicine · 2026Review
- Association of sarcopenia with survival and treatment response in brain metastasis of non-small cell lung cancer.Scientific reports · 2026Article
- Predictive value of changes in temporal muscle volume for 6-month functional outcome in patients with hypertensive intracerebral hemorrhage.Frontiers in neurology · 2026Article
- Does the interfascial temporalis flap increase muscle atrophy in pterional craniotomy? a comparative study with myocutaneous flap technique.Neurosurgical review · 2025Article
- Application of polyetheretherketone temporal muscle prostheses for temporal hollowing following cranioplasty.Frontiers in neurology · 2025Article
- Predictors of temporalis muscle atrophy and head asymmetry following frontotemporal craniotomy: A retrospective analysis of clinical factors and volumetric comparison.Surgical neurology international · 2025Article
- Acute Skeletal Muscle Wasting is Associated with Prolonged Hospital Stay in Critical Illness with Brain Injury.Neurocritical care · 2024Observational
- Initial Temporal Muscle Thickness and Area: Poor Predictors of Neurological Outcome in Aneurysmal Subarachnoid Hemorrhage in a Central European Patient Cohort.Journal of clinical medicine · 2023Article
- NimoTop or NimoStop?Neurocritical care · 2023Article
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntensive care unit (ICU) acquired weakness is a major contributor to poor functional outcome of ICU patients. Quantification of temporal muscle volume assessed on routine computed tomography (CT) scans may serve as a biomarker for muscle wasting in patients suffering from acute brain injury.
methodsThis is a retrospective analysis of prospectively collected data. Temporal muscle volume was assessed on head CT scans of consecutive patients with spontaneous subarachnoid hemorrhage within prespecified time frames (on admission, then weekly ± 2 days). Whenever possible, temporal muscle volume was assessed bilaterally and averaged for the analysis. Poor functional outcome was defined as a 3-month modified Rankin Scale Score ≥ 3. Statistical analysis was performed using generalized estimating equations to handle repeated measurements within individuals.
resultsThe analysis comprised 110 patients with a median Hunt & Hess score of 4 (interquartile range 3-5). Median age was 61 (50-70) years, 73 patients (66%) were women. Baseline temporal muscle volume was 18.5 ± 0.78 cm
conclusionsTemporal muscle volume, which is easily assessable on routine head CT scans, progressively decreases during the ICU stay after spontaneous subarachnoid hemorrhage. Because of its association with disease severity and functional outcome, it may serve as a biomarker for muscle wasting and outcome prognostication.
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