ArticleNature ecology & evolution2023
North African fox genomes show signatures of repeated introgression and adaptation to life in deserts.
Article in Nature ecology & evolution, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 42 citations in OpenAlex.
- Weak but Repeated Patterns of Co-Introgression of Nuclear OXPHOS Genes and Mitochondrial DNA in Iberian Wall Lizards.Genome biology and evolution · 2026Article
- On the ancestry and evolution of the extinct dire wolf.Cell genomics · 2026Article
- Multiple modes of selection underlie repeated and human-mediated adaptation in a formerly migratory fish.Molecular biology and evolution · 2026Article
- Multiple introgression events from ghost Rüppell's fox mitochondrial lineages into red fox.Scientific reports · 2026Article
- Article
- Degrees of convergent evolution in rodent adaptations to arid environments.Genome research · 2026Article
- Genomic divergence of leopards in the Cape Floristic Region of South Africa: potential drivers for local adaptation.Heredity · 2026Article
- INSIG1 parallel substitution drives lipid/sterol metabolic plasticity mediating desert adaptation in ungulates.Communications biology · 2026Article
- Genomic Insights into Hybridization and Speciation of Mitten Crabs in the Eriocheir Genus.Genomics, proteomics & bioinformatics · 2025Article
- Hybrid introgression as a mechanism of rapid evolution and resilience to climate change in a riparian tree species.Communications biology · 2025Article
- Genomic analyses support locally derived crown-of-thorns seastar outbreaks in the Pacific.BMC biology · 2025Article
- Inter-Island Whole-Genome Comparison Reveals Micro-Evolutionary Dynamics of the Red Fox, Stimulated Through Post-Glacial Sea-Level Alterations.Genome biology and evolution · 2025Article
- A high-quality genome assembly for a desert-adapted rodent, Merriam's kangaroo rat (Dipodomys merriami).The Journal of heredity · 2025Article
- Article
- Sex-biased Migration and Demographic History of the Big European Firefly Lampyris noctiluca.Molecular biology and evolution · 2025Article
- Dynamic interplay between niche variation and flight adaptability drove a hundred million years' dispersion in iconic lacewings.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Population genetic diversity and environmental adaptation of Tamarix hispida in the Tarim Basin, arid Northwestern China.Heredity · 2024Article
- Article
- The multi-tissue gene expression and physiological responses of water deprived Peromyscus eremicus.BMC genomics · 2024Article
- The ecological function of thyroid hormones.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
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Authors and funding
11 authors at 5 institutions in 6 countries.
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Abstract
Elucidating the evolutionary process of animal adaptation to deserts is key to understanding adaptive responses to climate change. Here we generated 82 individual whole genomes of four fox species (genus Vulpes) inhabiting the Sahara Desert at different evolutionary times. We show that adaptation of new colonizing species to a hot arid environment has probably been facilitated by introgression and trans-species polymorphisms shared with older desert resident species, including a putatively adaptive 25 Mb genomic region. Scans for signatures of selection implicated genes affecting temperature perception, non-renal water loss and heat production in the recent adaptation of North African red foxes (Vulpes vulpes), after divergence from Eurasian populations approximately 78 thousand years ago. In the extreme desert specialists, Rueppell's fox (V. rueppellii) and fennec (V. zerda), we identified repeated signatures of selection in genes affecting renal water homeostasis supported by gene expression and physiological differences. Our study provides insights into the mechanisms and genetic underpinnings of a natural experiment of repeated adaptation to extreme conditions.
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