ArticleSocial psychiatry and psychiatric epidemiology2024
Geographical variation in treated psychotic and other mental disorders in Finland by region and urbanicity.
Article in Social psychiatry and psychiatric epidemiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Time Trends in Excess Mortality Among Individuals With Bipolar Disorder in Finland, 2000-2023: A Nationwide Register Study.Bipolar disorders · 2026Article
- Household income and first psychiatric hospital admissions among children and adolescents.The International journal of social psychiatry · 2026Article
- Time Trends in Treated Incidence, Socio-demographic Risk Factors, and Co-occurring Psychiatric Disorders in Diagnosed Autism Spectrum Disorder With or Without Intellectual Disability: A Finnish Nationwide Register Study.Journal of autism and developmental disorders · 2025Article
- Lifetime incidence and age of onset of mental disorders, and 12-month service utilization in primary and secondary care: a Finnish nationwide registry study.Epidemiology and psychiatric sciences · 2025Article
- Parental psychiatric disorders and age-specific risk for offspring major depression: Finnish nationwide register-based study.Psychological medicine · 2025Article
- Prevalence of schizophrenia spectrum disorders in the Lazio region, Italy: use of an algorithm based on health administrative databases.BMC psychiatry · 2024Article
- Enhancing the accuracy of register-based metrics: Comparing methods for handling overlapping psychiatric register entries in Finnish healthcare registers.International journal of methods in psychiatric research · 2024Article
- Enhancing identification of nonaffective psychosis in register-based studies.Schizophrenia (Heidelberg, Germany) · 2024Article
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7 authors.
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Abstract
purposeIn Finland, prevalence of schizophrenia is higher in the eastern and northern regions and co-occurs with the distribution of schizophrenia polygenic risk scores. Both genetic and environmental factors have been hypothesized to contribute to this variation. We aimed to examine the prevalence of psychotic and other mental disorders by region and degree of urbanicity, and the impacts of socio-economic adjustments on these associations.
methodsNationwide population registers from 2011 to 2017 and healthcare registers from 1975 to 2017. We used 19 administrative and three aggregate regions based on the distribution of schizophrenia polygenic risk scores, and a seven-level urban-rural classification. Prevalence ratios (PRs) were calculated by Poisson regression models and adjusted for gender, age, and calendar year (basic adjustments), and Finnish origin, residential history, urbanicity, household income, economic activity, and physical comorbidity (additional adjustments) on an individual level. Average marginal effects were used to visualize interaction effects between region and urbanicity.
resultsA total of 5,898,180 individuals were observed. All mental disorders were slightly more prevalent (PR 1.03 [95% CI, 1.02-1.03]), and psychotic disorders (1.11 [1.10-1.12]) and schizophrenia (1.19 [1.17-1.21]) considerably more prevalent in eastern and northern than in western coastal regions. After the additional adjustments, however, the PRs were 0.95 (0.95-0.96), 1.00 (0.99-1.01), and 1.03 (1.02-1.04), respectively. Urban residence was associated with increased prevalence of psychotic disorders across all regions (adjusted PR 1.21 [1.20-1.22]).
conclusionAfter adjusting for socioeconomic and sociodemographic factors, the within-country distribution of mental disorders no longer followed the traditional east-west gradient. Urban-rural differences, on the other hand, persisted after the adjustments.
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