Evidence map›Paper›PMID 37308615›Full record

SynthesisHeart failure reviews2023

The prognostic value of right ventricular longitudinal strain in heart failure: a systematic review and meta-analysis.

Vasileios Anastasiou, Andreas S Papazoglou, Dimitrios V Moysidis, Stylianos Daios, Dimitrios Tsalikakis, George Giannakoulas, Theodoros Karamitsos, Victoria Delgado, Antonios Ziakas, Vasileios Kamperidis

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Heart failure reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

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  11. Haemodynamics and post-exercise recovery response in COPD-PH and ILD-PH: An appraisal.Lung India : official organ of Indian Chest Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Vasileios AnastasiouFirst Department of Cardiology, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, St. Kiriakidi 1, Thessaloniki, 54636, GR, Greece.
Andreas S PapazoglouFirst Department of Cardiology, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, St. Kiriakidi 1, Thessaloniki, 54636, GR, Greece.
Dimitrios V MoysidisFirst Department of Cardiology, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, St. Kiriakidi 1, Thessaloniki, 54636, GR, Greece.
Stylianos DaiosFirst Department of Cardiology, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, St. Kiriakidi 1, Thessaloniki, 54636, GR, Greece.
Dimitrios TsalikakisDepartment of Informatics and Telecommunication Engineering, University of Western Macedonia, Kozani, Greece.
George GiannakoulasFirst Department of Cardiology, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, St. Kiriakidi 1, Thessaloniki, 54636, GR, Greece.
Theodoros KaramitsosFirst Department of Cardiology, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, St. Kiriakidi 1, Thessaloniki, 54636, GR, Greece.
Victoria DelgadoDepartment of Cardiology, Hospital University Germans Triasi Pujol, Barcelona, Spain.
Antonios ZiakasFirst Department of Cardiology, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, St. Kiriakidi 1, Thessaloniki, 54636, GR, Greece.
Vasileios KamperidisFirst Department of Cardiology, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, St. Kiriakidi 1, Thessaloniki, 54636, GR, Greece. vkamperidis@outlook.com.ORCID 0000-0001-8424-6718
Aristotle University of Thessaloniki · GRHospital Universitari Germans Trias i Pujol · ESUniversity of Western Macedonia · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRight ventricular (RV) dysfunction is a well-recognized adverse prognostic feature in patients with heart failure (HF). Recently, many single-center studies have demonstrated that RV longitudinal strain assessed using speckle tracking echocardiography might be a powerful prognosticator in HF.

objectivesTo systematically appraise and quantitatively synthesize the evidence of the prognostic value of echocardiographic RV longitudinal strain, across the entire spectrum of left ventricular ejection function (LVEF) in HF.

methodsA systematic literature review was conducted in electronic databases to identify every study reporting the predictive role of RV global longitudinal strain (RV GLS) and RV free wall longitudinal strain (RV FWLS) in HF subjects. A random-effects meta-analysis was conducted to quantify the adjusted and unadjusted hazard ratios [(a)HRs] for all-cause-mortality and for the composite outcome of all-cause mortality or HF-related hospitalization for both indices.

resultsTwenty-four studies were deemed eligible and 15 of these provided appropriate quantitative data for the meta-analysis, encompassing 8,738 patients. Each 1% worsening in RV GLS and RV FWLS was independently associated with increased risk of all-cause mortality (pooled aHR = 1.08 [1.03-1.13]; p < 0.01; I

conclusionEchocardiographic RV GLS and RV FWLS appear to have powerful prognostic value across the range of HF.

Indexed as

Heart FailureHeart VentriclesStroke VolumeVentricular Dysfunction, RightVentricular Function, RightEchocardiographyHumansPrognosisVentricular Function, LeftHeart failureMeta-analysisRight ventricular strainSpeckle-tracking echocardiography

Identifiers

PMID37308615
PMCPMC10575809
OpenAlexW4380422884

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.