Evidence map›Paper›PMID 37308535›Full record

ReviewScientific reports2023

Disparity in the use of Alzheimer's disease treatment in Southern Brazil.

Maisa De Marco, Ana Laura Brandi, Andrei Bieger, Bárbara Krug, Analuiza Camozzato, Paulo D Picon, Marcia Lorena Fagundes Chaves, Raphael Machado Castilhos

Erratum issuedAbstract readReview
In one paragraph

Review in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Maisa De MarcoGraduate Program in Medical Sciences, Universidade Federal do Rio Grande Sul, Porto Alegre, Rio Grande do Sul, 90035003, Brazil.
Ana Laura BrandiFaculdade de Medicina, Universidade Federal do Rio Grande Sul, Porto Alegre, Rio Grande do Sul, 90035003, Brazil.
Andrei BiegerBiochemistry Department, Universidade Federal do Rio Grande Sul, Porto Alegre, Rio Grande do Sul, 90040060, Brazil.
Bárbara KrugSecretaria Estadual de Saúde do Estado do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, 90110150, Brazil.
Analuiza CamozzatoDepartment of Psychiatry, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Rio Grande do Sul, 90050170, Brazil.
Paulo D PiconDepartment of Internal Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, 90035903, Brazil.
Marcia Lorena Fagundes ChavesDepartment of Internal Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, 90035903, Brazil.
Raphael Machado CastilhosGraduate Program in Medical Sciences, Universidade Federal do Rio Grande Sul, Porto Alegre, Rio Grande do Sul, 90035003, Brazil. rcastilhos@hcpa.edu.br.ORCID http://orcid.org/0000-0002-1905-2084

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) treatment is freely available in the Brazilian public health system. However, the prescription pattern and its associated factors have been poorly studied in our country. We reviewed all granted requests for AD treatment in the public health system in October 2021 in the Rio Grande do Sul (RS) state, Southern Brazil. We performed a spatial autocorrelation analysis with the population-adjusted patients receiving any AD medication as the outcome and correlated it with several socioeconomic variables. 2382 patients with AD were being treated during the period analyzed. The distribution of the outcome variable was not random (Moran's I 0.17562, P <.0001), with the most developed regions having a higher number of patients/100,000 receiving any AD medication. We show that although AD medications are available through the public health system, there is a clear disparity between regions of RS state. Factors related to socioeconomic development partly explain this finding.

Indexed as

Alzheimer DiseaseBrazilHumansPrescriptionsPublic HealthSpatial Analysis

Identifiers

PMID37308535
PMCPMC10261112

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.