ArticleNature communications2023
Chemoselectivity change in catalytic hydrogenolysis enabling urea-reduction to formamide/amine over more reactive carbonyl compounds.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed, 30 citations in OpenAlex.
- A Tert-Alkyl Terephthalate Derivative as a Universal Degradable Unit for Condensation Polymers.Angewandte Chemie (International ed. in English) · 2026Article
- A General and Sustainable Strategy for the Depolymerization of Carbamates, Ureas, and Polyurethanes to Specialty Chemicals Enabled by Nickel.ChemSusChem · 2026Article
- Selective Degradation of Polyurethanes in Mixed Plastic Wastes via Ir-Catalyzed Hydrogenolysis.Angewandte Chemie (International ed. in English) · 2026Article
- The Influence of Incorporating Alkaline Metals on Alumina for Xylitol Hydrogenolysis over Ni Catalysts.ACS omega · 2026Article
- Mild and metal-free chemical recycling of polyureas via acylation-activated bond cleavage.National science review · 2025Article
- Hydrogenation of Carbamates, Ureas, and Polyurethanes Using Heterogeneous Catalysts.ACS sustainable chemistry & engineering · 2025Article
- Rising Opportunities in Catalytic Dehydrogenative Polymerization.ACS catalysis · 2025Review
- Degradation of a Wholly Aromatic Main-Chain Thermotropic Liquid-Crystalline Polymer Mediated by Superbases.JACS Au · 2024Article
- Counterintuitive chemoselectivity in the reduction of carbonyl compounds.Nature reviews. Chemistry · 2024Review
- Catalytic thiolation-depolymerization-like decomposition of oxyphenylene-type super engineering plastics via selective carbon-oxygen main chain cleavages.Communications chemistry · 2024Article
- Switching the hydrogenation selectivity of urea derivativesChemical science · 2024Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The selective transformation of a less reactive carbonyl moiety in the presence of more reactive ones can realize straightforward and environmentally benign chemical processes. However, such a transformation is highly challenging because the reactivity of carbonyl compounds, one of the most important functionalities in organic chemistry, depends on the substituents on the carbon atom. Herein, we report an Ir catalyst for the selective hydrogenolysis of urea derivatives, which are the least reactive carbonyl compounds, affording formamides and amines. Although formamide, as well as ester, amide, and carbamate substituents, are considered to be more reactive than urea, the proposed Ir catalyst tolerated these carbonyl groups and reacted with urea in a highly chemoselective manner. The proposed chemo- and regioselective hydrogenolysis allows the development of a strategy for the chemical recycling of polyurea resins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.