Evidence map›Paper›PMID 37308296›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023

Deletion of Transferrin Receptor 1 in Parvalbumin Interneurons Induces a Hereditary Spastic Paraplegia-Like Phenotype.

Wenchao Xiong, Liqiang Jin, Yulu Zhao, Yu Wu, Jinghua Dong, Zhixin Guo, Minzhen Zhu, Yongfeng Dai, Yida Pan, Xinhong Zhu

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Wenchao XiongSchool of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Liqiang JinSchool of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Yulu ZhaoSchool of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Yu WuSchool of Psychology, Shenzhen University, Shenzhen 518060, China.ORCID 0000-0003-0205-6529
Jinghua DongSchool of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Zhixin GuoSchool of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Minzhen ZhuSchool of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Yongfeng DaiSchool of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Yida PanSchool of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Xinhong ZhuSchool of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China zhuxh527@126.com.
Southern Medical University · CNShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hereditary spastic paraplegia (HSP) is a severe neurodegenerative movement disorder, the underlying pathophysiology of which remains poorly understood. Mounting evidence has suggested that iron homeostasis dysregulation can lead to motor function impairment. However, whether deficits in iron homeostasis are involved in the pathophysiology of HSP remains unknown. To address this knowledge gap, we focused on parvalbumin-positive (PV

Indexed as

Spastic Paraplegia, HereditaryAnimalsAtrophyFemaleInterneuronsMaleMiceParvalbuminsPhenotypeProteinsParvalbuminsProteinsaxon degenerationhereditary spastic paraplegiamotorparvalbuminspinal cordtransferrin receptor 1

Identifiers

PMID37308296
PMCPMC10325000
OpenAlexW4380303112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.